Recombinant multi-species DEK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
The Alternative Names of target: 1810019E15Rik,D13H6S231E,D6S231E,DEK,Dek,Protein DEK

Target products collectionGo to DEK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T28758-Ag-1/ GM-Tg-hg-T28758-Ag-2 Human DEK protein Human
GM-Tg-rg-T28758-Ag-1/ GM-Tg-rg-T28758-Ag-2 Rat DEK protein Rat
GM-Tg-mg-T28758-Ag-1/ GM-Tg-mg-T28758-Ag-2 Mouse DEK protein Mouse
GM-Tg-cynog-T28758-Ag-1/ GM-Tg-cynog-T28758-Ag-2 Cynomolgus/Rhesus macaque DEK protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T28758-Ag-1/ GM-Tg-felg-T28758-Ag-2 Feline DEK protein Feline
GM-Tg-cang-T28758-Ag-1/ GM-Tg-cang-T28758-Ag-2 Canine DEK protein Canine
GM-Tg-bovg-T28758-Ag-1/ GM-Tg-bovg-T28758-Ag-2 Bovine DEK protein Bovine
GM-Tg-equg-T28758-Ag-1/ GM-Tg-equg-T28758-Ag-2 Equine DEK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T28758-Ag-1/ GM-Tg-hg-T28758-Ag-2; GM-Tg-rg-T28758-Ag-1/ GM-Tg-rg-T28758-Ag-2;
GM-Tg-mg-T28758-Ag-1/ GM-Tg-mg-T28758-Ag-2; GM-Tg-cynog-T28758-Ag-1/ GM-Tg-cynog-T28758-Ag-2;
GM-Tg-felg-T28758-Ag-1/ GM-Tg-felg-T28758-Ag-2; GM-Tg-cang-T28758-Ag-1/ GM-Tg-cang-T28758-Ag-2;
GM-Tg-bovg-T28758-Ag-1/ GM-Tg-bovg-T28758-Ag-2; GM-Tg-equg-T28758-Ag-1/ GM-Tg-equg-T28758-Ag-2
Products Name DEK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DEK
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.