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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
| Target ID |
GM-T28758
|
| Target Name |
DEK
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7913
|
| Gene ID |
100066265 (Equus caballus), 101090769 (Felis catus), 110052 (Mus musculus), 306817 (Rattus norvegicus) 540945 (Bos taurus), 610538 (Canis lupus familiaris), 712460 (Macaca mulatta), 7913 (Homo sapiens)
|
| Target Alternative Names |
1810019E15Rik,D13H6S231E,D6S231E,DEK,Dek,Protein DEK
|
| Uniprot Accession |
Q7TNV0,Q6AXS3,P35659
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000012231, ENSMUSG00000021377, ENSBTAG00000012865, ENSCAFG00845028872, ENSMMUG00000019763, ENSG00000124795
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of DEK cDNA Clones/ORF Plasmid
DEK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7913 | Pre-made Human DEK/D6S231E siRNA oligo Duplex | 7913 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306817 | Pre-made Rat Dek siRNA oligo Duplex | 306817 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110052 | Pre-made Mouse Dek/D13H6S231E/1810019E15Rik siRNA oligo Duplex | 110052 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712460 | Pre-made Cynomolgus/Rhesus macaque DEK siRNA oligo Duplex | 712460 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090769 | Pre-made Cat/Feline DEK siRNA oligo Duplex | 101090769 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610538 | Pre-made Dog/Canine DEK siRNA oligo Duplex | 610538 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540945 | Pre-made Bovines/Cattle DEK siRNA oligo Duplex | 540945 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066265 | Pre-made Equine/Horse DEK siRNA oligo Duplex | 100066265 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DEK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28758-Ab | Human | Anti-Human DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28758-Ab | Rat | Anti-Rat DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28758-Ab | Mouse | Anti-Mouse DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28758-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28758-Ab | Cat/Feline | Anti-Cat/Feline DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28758-Ab | Dog/Canine | Anti-Dog/Canine DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28758-Ab | Bovines/Cattle | Anti-Bovines/Cattle DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28758-Ab | Equine/Horse | Anti-Equine/Horse DEK monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DEK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28758-Ag | Human | Human DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T28758-Ag | Rat | Rat DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T28758-Ag | Mouse | Mouse DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T28758-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T28758-Ag | Cat/Feline | Cat/Feline DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T28758-Ag | Dog/Canine | Dog/Canine DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T28758-Ag | Bovines/Cattle | Bovines/Cattle DEK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T28758-Ag | Equine/Horse | Equine/Horse DEK recombinant protein | Mammalian cell | Detail |