Recombinant multi-species AKR1B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKR1B1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
The Alternative Names of target: ADR,AKR1B1,ALDR1,ALDRED,ALR-P-I,ALR2,AR,Ahr-1,Ahr1,Akr1b1,Akr1b3,Akr1b4,Aldehyde reductase,Aldo-keto reductase family 1 member B1,Aldor1,Aldose reductase (AR),Aldr1,Alr,RATALDRED

Target products collectionGo to AKR1B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T26623-Ag-1/ GM-Tg-hg-T26623-Ag-2 Human AKR1B1 protein Human
GM-Tg-rg-T26623-Ag-1/ GM-Tg-rg-T26623-Ag-2 Rat AKR1B1 protein Rat
GM-Tg-mg-T26623-Ag-1/ GM-Tg-mg-T26623-Ag-2 Mouse AKR1B1 protein Mouse
GM-Tg-cynog-T26623-Ag-1/ GM-Tg-cynog-T26623-Ag-2 Cynomolgus/Rhesus macaque AKR1B1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T26623-Ag-1/ GM-Tg-felg-T26623-Ag-2 Feline AKR1B1 protein Feline
GM-Tg-cang-T26623-Ag-1/ GM-Tg-cang-T26623-Ag-2 Canine AKR1B1 protein Canine
GM-Tg-bovg-T26623-Ag-1/ GM-Tg-bovg-T26623-Ag-2 Bovine AKR1B1 protein Bovine
GM-Tg-equg-T26623-Ag-1/ GM-Tg-equg-T26623-Ag-2 Equine AKR1B1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T26623-Ag-1/ GM-Tg-hg-T26623-Ag-2; GM-Tg-rg-T26623-Ag-1/ GM-Tg-rg-T26623-Ag-2;
GM-Tg-mg-T26623-Ag-1/ GM-Tg-mg-T26623-Ag-2; GM-Tg-cynog-T26623-Ag-1/ GM-Tg-cynog-T26623-Ag-2;
GM-Tg-felg-T26623-Ag-1/ GM-Tg-felg-T26623-Ag-2; GM-Tg-cang-T26623-Ag-1/ GM-Tg-cang-T26623-Ag-2;
GM-Tg-bovg-T26623-Ag-1/ GM-Tg-bovg-T26623-Ag-2; GM-Tg-equg-T26623-Ag-1/ GM-Tg-equg-T26623-Ag-2
Products Name AKR1B1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AKR1B1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKR1B1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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