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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
| Target ID |
GM-T26623
|
| Target Name |
AKR1B1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
231
|
| Gene ID |
100065145 (Equus caballus), 101095406 (Felis catus), 11677 (Mus musculus), 231 (Homo sapiens) 24192 (Rattus norvegicus), 607537 (Canis lupus familiaris)
|
| Target Alternative Names |
ADR,AKR1B1,ALDR1,ALDRED,ALR-P-I,ALR2,AR,Ahr-1,Ahr1,Akr1b1,Akr1b3,Akr1b4,Aldehyde reductase,Aldo-keto reductase family 1 member B1,Aldor1,Aldose reductase (AR),Aldr1,Alr,RATALDRED
|
| Uniprot Accession |
P45376,P15121,P07943
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Breast Cancer
|
| Disease from KEGG |
Metabolic pathways, Pentose and glucuronate interconversions
|
| Gene Ensembl |
ENSECAG00000014271, ENSMUSG00000001642, ENSG00000085662, ENSCAFG00845014537
|
Pre-made viral vector of AKR1B1 cDNA Clones/ORF Plasmid
AKR1B1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo231 | Pre-made Human AKR1B1/AR/ADR siRNA oligo Duplex | 231 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24192 | Pre-made Rat Akr1b1/Alr/Aldr1 siRNA oligo Duplex | 24192 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11677 | Pre-made Mouse Akr1b1/AR/ALR2 siRNA oligo Duplex | 11677 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095406 | Pre-made Cat/Feline AKR1B1 siRNA oligo Duplex | 101095406 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607537 | Pre-made Dog/Canine AKR1B1 siRNA oligo Duplex | 607537 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065145 | Pre-made Equine/Horse AKR1B1 siRNA oligo Duplex | 100065145 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AKR1B1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26623-Ab | Human | Anti-Human AKR1B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26623-Ab | Rat | Anti-Rat AKR1B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26623-Ab | Mouse | Anti-Mouse AKR1B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26623-Ab | Cat/Feline | Anti-Cat/Feline AKR1B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26623-Ab | Dog/Canine | Anti-Dog/Canine AKR1B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26623-Ab | Equine/Horse | Anti-Equine/Horse AKR1B1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
AKR1B1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26623-Ag | Human | Human AKR1B1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T26623-Ag | Rat | Rat AKR1B1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T26623-Ag | Mouse | Mouse AKR1B1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T26623-Ag | Cat/Feline | Cat/Feline AKR1B1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T26623-Ag | Dog/Canine | Dog/Canine AKR1B1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T26623-Ag | Equine/Horse | Equine/Horse AKR1B1 recombinant protein | Mammalian cell | Detail |