Recombinant multi-species p300/EP300 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine p300/EP300 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
The Alternative Names of target: p300, EP300,Histone acetyltransferase p300,p300 HAT,E1A-associated protein p300, Histone butyryltransferase p300, Histone crotonyltransferase p300, Protein 2-hydroxyisobutyryltransferase p300, Protein lactyltransferas p300, Protein propionyltransferase p300,p300,KAT3B,MKHK2,RSTS2

Target products collectionGo to p300/EP300 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T25956-Ab-1/ GM-Tg-hg-T25956-Ab-2 Human p300/EP300 protein Human
GM-Tg-rg-T25956-Ab-1/ GM-Tg-rg-T25956-Ab-2 Rat p300/EP300 protein Rat
GM-Tg-mg-T25956-Ab-1/ GM-Tg-mg-T25956-Ab-2 Mouse p300/EP300 protein Mouse
GM-Tg-cynog-T25956-Ab-1/ GM-Tg-cynog-T25956-Ab-2 Cynomolgus/Rhesus macaque p300/EP300 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T25956-Ab-1/ GM-Tg-felg-T25956-Ab-2 Feline p300/EP300 protein Feline
GM-Tg-cang-T25956-Ab-1/ GM-Tg-cang-T25956-Ab-2 Canine p300/EP300 protein Canine
GM-Tg-bovg-T25956-Ab-1/ GM-Tg-bovg-T25956-Ab-2 Bovine p300/EP300 protein Bovine
GM-Tg-equg-T25956-Ab-1/ GM-Tg-equg-T25956-Ab-2 Equine p300/EP300 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T25956-Ab-1/ GM-Tg-hg-T25956-Ab-2; GM-Tg-rg-T25956-Ab-1/ GM-Tg-rg-T25956-Ab-2;
GM-Tg-mg-T25956-Ab-1/ GM-Tg-mg-T25956-Ab-2; GM-Tg-cynog-T25956-Ab-1/ GM-Tg-cynog-T25956-Ab-2;
GM-Tg-felg-T25956-Ab-1/ GM-Tg-felg-T25956-Ab-2; GM-Tg-cang-T25956-Ab-1/ GM-Tg-cang-T25956-Ab-2;
GM-Tg-bovg-T25956-Ab-1/ GM-Tg-bovg-T25956-Ab-2; GM-Tg-equg-T25956-Ab-1/ GM-Tg-equg-T25956-Ab-2
Products Name p300/EP300 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name p300/EP300
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine p300/EP300 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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