Explore p300/EP300 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T25956
|
| Target Name |
p300/EP300
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2033
|
| Gene ID |
100055626 (Equus caballus), 100684945 (Canis lupus familiaris), 101088344 (Felis catus), 112446776 (Bos taurus)
170915 (Rattus norvegicus), 2033 (Homo sapiens), 328572 (Mus musculus), 706258 (Macaca mulatta)
|
| Target Alternative Names |
EP300,Ep300,p300,KAT3B,MKHK2,RSTS2,p300 HAT,A430090G16,A730011L11
|
| Uniprot Accession |
Q09472,B2RWS6
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Wnt signaling pathway, TGF-beta signaling pathway, Adherens junction, JAK-STAT signaling pathway, Long-term potentiation, Melanogenesis, Thyroid hormone signaling pathway, Growth hormone synthesis, secretion and action, Tuberculosis, Hepatitis B, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Renal cell carcinoma, Prostate cancer
|
| Gene Ensembl |
ENSECAG00000009327, ENSCAFG00845018383, ENSBTAG00000016198, ENSG00000100393, ENSMUSG00000055024, ENSMMUG00000000893
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of p300/EP300 cDNA Clones/ORF Plasmid
p300/EP300 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2033 | Pre-made Human EP300/p300/KAT3B siRNA oligo Duplex | 2033 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170915 | Pre-made Rat Ep300 siRNA oligo Duplex | 170915 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo328572 | Pre-made Mouse Ep300/p300/KAT3B siRNA oligo Duplex | 328572 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706258 | Pre-made Cynomolgus/Rhesus macaque EP300 siRNA oligo Duplex | 706258 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088344 | Pre-made Cat/Feline EP300 siRNA oligo Duplex | 101088344 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100684945 | Pre-made Dog/Canine EP300 siRNA oligo Duplex | 100684945 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo112446776 | Pre-made Bovines/Cattle EP300 siRNA oligo Duplex | 112446776 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055626 | Pre-made Equine/Horse EP300 siRNA oligo Duplex | 100055626 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
p300/EP300 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T25956-Ab | Human | Anti-Human p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T25956-Ab | Rat | Anti-Rat p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T25956-Ab | Mouse | Anti-Mouse p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T25956-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T25956-Ab | Cat/Feline | Anti-Cat/Feline p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T25956-Ab | Dog/Canine | Anti-Dog/Canine p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T25956-Ab | Bovines/Cattle | Anti-Bovines/Cattle p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T25956-Ab | Equine/Horse | Anti-Equine/Horse p300/EP300 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
p300/EP300 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T25956-Ag | Human | Human p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T25956-Ag | Rat | Rat p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T25956-Ag | Mouse | Mouse p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T25956-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T25956-Ag | Cat/Feline | Cat/Feline p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T25956-Ag | Dog/Canine | Dog/Canine p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T25956-Ag | Bovines/Cattle | Bovines/Cattle p300/EP300 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T25956-Ag | Equine/Horse | Equine/Horse p300/EP300 recombinant protein | Mammalian cell | Detail |
