Recombinant multi-species EZH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EZH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
The Alternative Names of target: ENX-1,ENX1,EZH2,EZH2b,Enhancer of zeste homolog 2,Enx-1,Enx1h,Ezh2,Histone-lysine N-methyltransferase EZH2,KMT6,KMT6A,Lysine N-methyltransferase 6,WVS,WVS2,mKIAA4065
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T25265-Ag-1/ GM-Tg-hg-T25265-Ag-2 | Human EZH2 protein | Human |
| GM-Tg-rg-T25265-Ag-1/ GM-Tg-rg-T25265-Ag-2 | Rat EZH2 protein | Rat |
| GM-Tg-mg-T25265-Ag-1/ GM-Tg-mg-T25265-Ag-2 | Mouse EZH2 protein | Mouse |
| GM-Tg-cynog-T25265-Ag-1/ GM-Tg-cynog-T25265-Ag-2 | Cynomolgus/Rhesus macaque EZH2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T25265-Ag-1/ GM-Tg-felg-T25265-Ag-2 | Feline EZH2 protein | Feline |
| GM-Tg-cang-T25265-Ag-1/ GM-Tg-cang-T25265-Ag-2 | Canine EZH2 protein | Canine |
| GM-Tg-bovg-T25265-Ag-1/ GM-Tg-bovg-T25265-Ag-2 | Bovine EZH2 protein | Bovine |
| GM-Tg-equg-T25265-Ag-1/ GM-Tg-equg-T25265-Ag-2 | Equine EZH2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T25265-Ag-1/ GM-Tg-hg-T25265-Ag-2;
GM-Tg-rg-T25265-Ag-1/ GM-Tg-rg-T25265-Ag-2;
GM-Tg-mg-T25265-Ag-1/ GM-Tg-mg-T25265-Ag-2; GM-Tg-cynog-T25265-Ag-1/ GM-Tg-cynog-T25265-Ag-2; GM-Tg-felg-T25265-Ag-1/ GM-Tg-felg-T25265-Ag-2; GM-Tg-cang-T25265-Ag-1/ GM-Tg-cang-T25265-Ag-2; GM-Tg-bovg-T25265-Ag-1/ GM-Tg-bovg-T25265-Ag-2; GM-Tg-equg-T25265-Ag-1/ GM-Tg-equg-T25265-Ag-2 |
| Products Name | EZH2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | EZH2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EZH2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.