Explore EZH2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
| Target ID |
GM-T25265
|
| Target Name |
EZH2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2146
|
| Gene ID |
100051290 (Equus caballus), 101087309 (Felis catus), 14056 (Mus musculus), 2146 (Homo sapiens)
312299 (Rattus norvegicus), 475511 (Canis lupus familiaris), 509106 (Bos taurus), 709075 (Macaca mulatta)
|
| Target Alternative Names |
ENX-1,ENX1,EZH2,EZH2b,Enhancer of zeste homolog 2,Enx-1,Enx1h,Ezh2,Histone-lysine N-methyltransferase EZH2,KMT6,KMT6A,Lysine N-methyltransferase 6,WVS,WVS2,mKIAA4065
|
| Uniprot Accession |
Q61188,Q15910
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000021529, ENSMUSG00000029687, ENSG00000106462, ENSCAFG00845012096, ENSBTAG00000009426, ENSMMUG00000013494
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of EZH2 cDNA Clones/ORF Plasmid
EZH2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2146 | Pre-made Human EZH2/WVS/ENX1 siRNA oligo Duplex | 2146 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312299 | Pre-made Rat Ezh2 siRNA oligo Duplex | 312299 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14056 | Pre-made Mouse Ezh2/KMT6/Enx-1 siRNA oligo Duplex | 14056 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709075 | Pre-made Cynomolgus/Rhesus macaque EZH2 siRNA oligo Duplex | 709075 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087309 | Pre-made Cat/Feline EZH2 siRNA oligo Duplex | 101087309 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475511 | Pre-made Dog/Canine EZH2 siRNA oligo Duplex | 475511 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509106 | Pre-made Bovines/Cattle EZH2 siRNA oligo Duplex | 509106 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051290 | Pre-made Equine/Horse EZH2 siRNA oligo Duplex | 100051290 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EZH2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T25265-Ab | Human | Anti-Human EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T25265-Ab | Rat | Anti-Rat EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T25265-Ab | Mouse | Anti-Mouse EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T25265-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T25265-Ab | Cat/Feline | Anti-Cat/Feline EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T25265-Ab | Dog/Canine | Anti-Dog/Canine EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T25265-Ab | Bovines/Cattle | Anti-Bovines/Cattle EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T25265-Ab | Equine/Horse | Anti-Equine/Horse EZH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
EZH2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T25265-Ag | Human | Human EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T25265-Ag | Rat | Rat EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T25265-Ag | Mouse | Mouse EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T25265-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T25265-Ag | Cat/Feline | Cat/Feline EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T25265-Ag | Dog/Canine | Dog/Canine EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T25265-Ag | Bovines/Cattle | Bovines/Cattle EZH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T25265-Ag | Equine/Horse | Equine/Horse EZH2 recombinant protein | Mammalian cell | Detail |
