Recombinant multi-species MAPK3/ERK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPK3/ERK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ERK-1,ERK1,ERT2,Erk-1,Erk1,Ert2,Esrk1,Extracellular signal-regulated kinase 1 (ERK-1),HS44KDAP,HUMKER1A,Insulin-stimulated MAP2 kinase,MAP kinase 3,MAP kinase isoform p44 (p44-MAPK),MAPK 3,MAPK1,MAPK3,MNK1,Mapk3,Microtubule-associated protein 2 kinase,Mitogen-activated protein kinase 3,Mnk1,Mtap2k,P44ERK1,P44MAPK,PRKM3,Prkm3,p44,p44-ERK1,p44-MAPK,p44erk1,p44mapk
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T23276-Ag-1/ GM-Tg-hg-T23276-Ag-2 | Human MAPK3/ERK1 protein | Human |
| GM-Tg-rg-T23276-Ag-1/ GM-Tg-rg-T23276-Ag-2 | Rat MAPK3/ERK1 protein | Rat |
| GM-Tg-mg-T23276-Ag-1/ GM-Tg-mg-T23276-Ag-2 | Mouse MAPK3/ERK1 protein | Mouse |
| GM-Tg-cynog-T23276-Ag-1/ GM-Tg-cynog-T23276-Ag-2 | Cynomolgus/Rhesus macaque MAPK3/ERK1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T23276-Ag-1/ GM-Tg-felg-T23276-Ag-2 | Feline MAPK3/ERK1 protein | Feline |
| GM-Tg-cang-T23276-Ag-1/ GM-Tg-cang-T23276-Ag-2 | Canine MAPK3/ERK1 protein | Canine |
| GM-Tg-bovg-T23276-Ag-1/ GM-Tg-bovg-T23276-Ag-2 | Bovine MAPK3/ERK1 protein | Bovine |
| GM-Tg-equg-T23276-Ag-1/ GM-Tg-equg-T23276-Ag-2 | Equine MAPK3/ERK1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T23276-Ag-1/ GM-Tg-hg-T23276-Ag-2;
GM-Tg-rg-T23276-Ag-1/ GM-Tg-rg-T23276-Ag-2;
GM-Tg-mg-T23276-Ag-1/ GM-Tg-mg-T23276-Ag-2; GM-Tg-cynog-T23276-Ag-1/ GM-Tg-cynog-T23276-Ag-2; GM-Tg-felg-T23276-Ag-1/ GM-Tg-felg-T23276-Ag-2; GM-Tg-cang-T23276-Ag-1/ GM-Tg-cang-T23276-Ag-2; GM-Tg-bovg-T23276-Ag-1/ GM-Tg-bovg-T23276-Ag-2; GM-Tg-equg-T23276-Ag-1/ GM-Tg-equg-T23276-Ag-2 |
| Products Name | MAPK3/ERK1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | MAPK3/ERK1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAPK3/ERK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.