Recombinant multi-species PR/Progesterone Receptor/PGR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PR/Progesterone Receptor/PGR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
The Alternative Names of target: 9930019P03Rik,NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PR-A,PR-B,Pgr,Progesterone Receptor,Progesterone receptor
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T22939-Ag-1/ GM-Tg-hg-T22939-Ag-2 | Human PR/Progesterone Receptor/PGR protein | Human |
| GM-Tg-rg-T22939-Ag-1/ GM-Tg-rg-T22939-Ag-2 | Rat PR/Progesterone Receptor/PGR protein | Rat |
| GM-Tg-mg-T22939-Ag-1/ GM-Tg-mg-T22939-Ag-2 | Mouse PR/Progesterone Receptor/PGR protein | Mouse |
| GM-Tg-cynog-T22939-Ag-1/ GM-Tg-cynog-T22939-Ag-2 | Cynomolgus/Rhesus macaque PR/Progesterone Receptor/PGR protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T22939-Ag-1/ GM-Tg-felg-T22939-Ag-2 | Feline PR/Progesterone Receptor/PGR protein | Feline |
| GM-Tg-cang-T22939-Ag-1/ GM-Tg-cang-T22939-Ag-2 | Canine PR/Progesterone Receptor/PGR protein | Canine |
| GM-Tg-bovg-T22939-Ag-1/ GM-Tg-bovg-T22939-Ag-2 | Bovine PR/Progesterone Receptor/PGR protein | Bovine |
| GM-Tg-equg-T22939-Ag-1/ GM-Tg-equg-T22939-Ag-2 | Equine PR/Progesterone Receptor/PGR protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T22939-Ag-1/ GM-Tg-hg-T22939-Ag-2;
GM-Tg-rg-T22939-Ag-1/ GM-Tg-rg-T22939-Ag-2;
GM-Tg-mg-T22939-Ag-1/ GM-Tg-mg-T22939-Ag-2; GM-Tg-cynog-T22939-Ag-1/ GM-Tg-cynog-T22939-Ag-2; GM-Tg-felg-T22939-Ag-1/ GM-Tg-felg-T22939-Ag-2; GM-Tg-cang-T22939-Ag-1/ GM-Tg-cang-T22939-Ag-2; GM-Tg-bovg-T22939-Ag-1/ GM-Tg-bovg-T22939-Ag-2; GM-Tg-equg-T22939-Ag-1/ GM-Tg-equg-T22939-Ag-2 |
| Products Name | PR/Progesterone Receptor/PGR protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PR/Progesterone Receptor/PGR |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PR/Progesterone Receptor/PGR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.