Recombinant multi-species PR/Progesterone Receptor/PGR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PR/Progesterone Receptor/PGR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
The Alternative Names of target: 9930019P03Rik,NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PR-A,PR-B,Pgr,Progesterone Receptor,Progesterone receptor

Target products collectionGo to PR/Progesterone Receptor/PGR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T22939-Ag-1/ GM-Tg-hg-T22939-Ag-2 Human PR/Progesterone Receptor/PGR protein Human
GM-Tg-rg-T22939-Ag-1/ GM-Tg-rg-T22939-Ag-2 Rat PR/Progesterone Receptor/PGR protein Rat
GM-Tg-mg-T22939-Ag-1/ GM-Tg-mg-T22939-Ag-2 Mouse PR/Progesterone Receptor/PGR protein Mouse
GM-Tg-cynog-T22939-Ag-1/ GM-Tg-cynog-T22939-Ag-2 Cynomolgus/Rhesus macaque PR/Progesterone Receptor/PGR protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T22939-Ag-1/ GM-Tg-felg-T22939-Ag-2 Feline PR/Progesterone Receptor/PGR protein Feline
GM-Tg-cang-T22939-Ag-1/ GM-Tg-cang-T22939-Ag-2 Canine PR/Progesterone Receptor/PGR protein Canine
GM-Tg-bovg-T22939-Ag-1/ GM-Tg-bovg-T22939-Ag-2 Bovine PR/Progesterone Receptor/PGR protein Bovine
GM-Tg-equg-T22939-Ag-1/ GM-Tg-equg-T22939-Ag-2 Equine PR/Progesterone Receptor/PGR protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T22939-Ag-1/ GM-Tg-hg-T22939-Ag-2; GM-Tg-rg-T22939-Ag-1/ GM-Tg-rg-T22939-Ag-2;
GM-Tg-mg-T22939-Ag-1/ GM-Tg-mg-T22939-Ag-2; GM-Tg-cynog-T22939-Ag-1/ GM-Tg-cynog-T22939-Ag-2;
GM-Tg-felg-T22939-Ag-1/ GM-Tg-felg-T22939-Ag-2; GM-Tg-cang-T22939-Ag-1/ GM-Tg-cang-T22939-Ag-2;
GM-Tg-bovg-T22939-Ag-1/ GM-Tg-bovg-T22939-Ag-2; GM-Tg-equg-T22939-Ag-1/ GM-Tg-equg-T22939-Ag-2
Products Name PR/Progesterone Receptor/PGR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PR/Progesterone Receptor/PGR
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PR/Progesterone Receptor/PGR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.