Explore PR/Progesterone Receptor/PGR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T22939
|
| Target Name |
PR/Progesterone Receptor/PGR
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5241
|
| Gene ID |
100033883 (Equus caballus), 100848466 (Bos taurus), 101098742 (Felis catus), 18667 (Mus musculus) 25154 (Rattus norvegicus), 403621 (Canis lupus familiaris), 5241 (Homo sapiens), 613024 (Macaca mulatta)
|
| Target Alternative Names |
9930019P03Rik,NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PR-A,PR-B,Pgr,Progesterone Receptor,Progesterone receptor
|
| Uniprot Accession |
Q00175,Q63449,Q9GLW0,P06401
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
prostate cancer
|
| Disease from KEGG |
Chemical carcinogenesis - receptor activation, Breast cancer
|
| Gene Ensembl |
ENSECAG00000011511, ENSBTAG00000024648, ENSMUSG00000031870, ENSCAFG00845015739, ENSG00000082175, ENSMMUG00000011846
|
PR/Progesterone Receptor/PGR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5241 | Pre-made Human PGR/PR/NR3C3 siRNA oligo Duplex | 5241 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25154 | Pre-made Rat Pgr siRNA oligo Duplex | 25154 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18667 | Pre-made Mouse Pgr/PR/PR-A siRNA oligo Duplex | 18667 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613024 | Pre-made Cynomolgus/Rhesus macaque PGR/PR siRNA oligo Duplex | 613024 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098742 | Pre-made Cat/Feline PGR siRNA oligo Duplex | 101098742 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403621 | Pre-made Dog/Canine PGR/PR siRNA oligo Duplex | 403621 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100848466 | Pre-made Bovines/Cattle PGR siRNA oligo Duplex | 100848466 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033883 | Pre-made Equine/Horse PGR/PR siRNA oligo Duplex | 100033883 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PR/Progesterone Receptor/PGR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22939-Ab | Human | Anti-Human PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T22939-Ab | Rat | Anti-Rat PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T22939-Ab | Mouse | Anti-Mouse PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22939-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T22939-Ab | Cat/Feline | Anti-Cat/Feline PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T22939-Ab | Dog/Canine | Anti-Dog/Canine PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T22939-Ab | Bovines/Cattle | Anti-Bovines/Cattle PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T22939-Ab | Equine/Horse | Anti-Equine/Horse PR/Progesterone Receptor/PGR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PR/Progesterone Receptor/PGR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22939-Ag | Human | Human PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T22939-Ag | Rat | Rat PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T22939-Ag | Mouse | Mouse PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T22939-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T22939-Ag | Cat/Feline | Cat/Feline PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T22939-Ag | Dog/Canine | Dog/Canine PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T22939-Ag | Bovines/Cattle | Bovines/Cattle PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T22939-Ag | Equine/Horse | Equine/Horse PR/Progesterone Receptor/PGR recombinant protein | Mammalian cell | Detail |