Recombinant multi-species MFG-E8/Medin/MFGE8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MFG-E8/Medin/MFGE8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
The Alternative Names of target: AGS,BA46,Breast epithelial antigen BA46,EDIL1,HMFG,HsT19888,Lactadherin,MFG-E8,MFGE-8,MFGE8,MFGM,MFGME8,MFGMP-E8,MP47,Medin,Mfge8,Mfgm,Milk fat globule-EGF factor 8 (MFG-E8),OAcGD3S,P47,SED1,SPAG10,hP47,lactadherin

Target products collectionGo to MFG-E8/Medin/MFGE8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T22538-Ag-1/ GM-Tg-hg-T22538-Ag-2 Human MFG-E8/Medin/MFGE8 protein Human
GM-Tg-rg-T22538-Ag-1/ GM-Tg-rg-T22538-Ag-2 Rat MFG-E8/Medin/MFGE8 protein Rat
GM-Tg-mg-T22538-Ag-1/ GM-Tg-mg-T22538-Ag-2 Mouse MFG-E8/Medin/MFGE8 protein Mouse
GM-Tg-cynog-T22538-Ag-1/ GM-Tg-cynog-T22538-Ag-2 Cynomolgus/Rhesus macaque MFG-E8/Medin/MFGE8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T22538-Ag-1/ GM-Tg-felg-T22538-Ag-2 Feline MFG-E8/Medin/MFGE8 protein Feline
GM-Tg-cang-T22538-Ag-1/ GM-Tg-cang-T22538-Ag-2 Canine MFG-E8/Medin/MFGE8 protein Canine
GM-Tg-bovg-T22538-Ag-1/ GM-Tg-bovg-T22538-Ag-2 Bovine MFG-E8/Medin/MFGE8 protein Bovine
GM-Tg-equg-T22538-Ag-1/ GM-Tg-equg-T22538-Ag-2 Equine MFG-E8/Medin/MFGE8 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T22538-Ag-1/ GM-Tg-hg-T22538-Ag-2; GM-Tg-rg-T22538-Ag-1/ GM-Tg-rg-T22538-Ag-2;
GM-Tg-mg-T22538-Ag-1/ GM-Tg-mg-T22538-Ag-2; GM-Tg-cynog-T22538-Ag-1/ GM-Tg-cynog-T22538-Ag-2;
GM-Tg-felg-T22538-Ag-1/ GM-Tg-felg-T22538-Ag-2; GM-Tg-cang-T22538-Ag-1/ GM-Tg-cang-T22538-Ag-2;
GM-Tg-bovg-T22538-Ag-1/ GM-Tg-bovg-T22538-Ag-2; GM-Tg-equg-T22538-Ag-1/ GM-Tg-equg-T22538-Ag-2
Products Name MFG-E8/Medin/MFGE8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MFG-E8/Medin/MFGE8
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MFG-E8/Medin/MFGE8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.