Explore MFG-E8/Medin/MFGE8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
| Target ID |
GM-T22538
|
| Target Name |
MFG-E8/Medin/MFGE8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4240
|
| Gene ID |
100033943 (Equus caballus), 101091372 (Felis catus), 17304 (Mus musculus), 25277 (Rattus norvegicus)
281913 (Bos taurus), 4240 (Homo sapiens), 488730 (Canis lupus familiaris), 703501 (Macaca mulatta)
|
| Target Alternative Names |
AGS,BA46,Breast epithelial antigen BA46,EDIL1,HMFG,HsT19888,Lactadherin,MFG-E8,MFGE-8,MFGE8,MFGM,MFGME8,MFGMP-E8,MP47,Medin,Mfge8,Mfgm,Milk fat globule-EGF factor 8 (MFG-E8),OAcGD3S,P47,SED1,SPAG10,hP47,lactadherin
|
| Uniprot Accession |
P21956,P70490,Q95114,Q08431
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000018875, ENSMUSG00000030605, ENSBTAG00000003300, ENSG00000140545, ENSCAFG00845003786, ENSMMUG00000043001
|
Pre-made viral vector of MFG-E8/Medin/MFGE8 cDNA Clones/ORF Plasmid
MFG-E8/Medin/MFGE8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4240 | Pre-made Human MFGE8/BA46/HMFG siRNA oligo Duplex | 4240 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25277 | Pre-made Rat Mfge8/AGS/MFGME8 siRNA oligo Duplex | 25277 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17304 | Pre-made Mouse Mfge8/P47/MP47 siRNA oligo Duplex | 17304 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703501 | Pre-made Cynomolgus/Rhesus macaque MFGE8 siRNA oligo Duplex | 703501 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091372 | Pre-made Cat/Feline MFGE8 siRNA oligo Duplex | 101091372 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488730 | Pre-made Dog/Canine MFGE8 siRNA oligo Duplex | 488730 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281913 | Pre-made Bovines/Cattle MFGE8 siRNA oligo Duplex | 281913 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033943 | Pre-made Equine/Horse MFGE8/MFGE-8 siRNA oligo Duplex | 100033943 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MFG-E8/Medin/MFGE8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22538-Ab | Human | Anti-Human MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T22538-Ab | Rat | Anti-Rat MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T22538-Ab | Mouse | Anti-Mouse MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22538-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T22538-Ab | Cat/Feline | Anti-Cat/Feline MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T22538-Ab | Dog/Canine | Anti-Dog/Canine MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T22538-Ab | Bovines/Cattle | Anti-Bovines/Cattle MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T22538-Ab | Equine/Horse | Anti-Equine/Horse MFG-E8/Medin/MFGE8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MFG-E8/Medin/MFGE8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22538-Ag | Human | Human MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T22538-Ag | Rat | Rat MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T22538-Ag | Mouse | Mouse MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T22538-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T22538-Ag | Cat/Feline | Cat/Feline MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T22538-Ag | Dog/Canine | Dog/Canine MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T22538-Ag | Bovines/Cattle | Bovines/Cattle MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T22538-Ag | Equine/Horse | Equine/Horse MFG-E8/Medin/MFGE8 recombinant protein | Mammalian cell | Detail |
