Recombinant multi-species GAD65/GAD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GAD65/GAD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
The Alternative Names of target: 6330404F12Rik,65 kDa glutamic acid decarboxylase (GAD-65),GAD(65),GAD2,GAD65,Gad-2,Gad2,Glutamate decarboxylase 2,Glutamate decarboxylase 65 kDa isoform,gad65

Target products collectionGo to GAD65/GAD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T22128-Ag-1/ GM-Tg-hg-T22128-Ag-2 Human GAD65/GAD2 protein Human
GM-Tg-rg-T22128-Ag-1/ GM-Tg-rg-T22128-Ag-2 Rat GAD65/GAD2 protein Rat
GM-Tg-mg-T22128-Ag-1/ GM-Tg-mg-T22128-Ag-2 Mouse GAD65/GAD2 protein Mouse
GM-Tg-cynog-T22128-Ag-1/ GM-Tg-cynog-T22128-Ag-2 Cynomolgus/Rhesus macaque GAD65/GAD2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T22128-Ag-1/ GM-Tg-felg-T22128-Ag-2 Feline GAD65/GAD2 protein Feline
GM-Tg-cang-T22128-Ag-1/ GM-Tg-cang-T22128-Ag-2 Canine GAD65/GAD2 protein Canine
GM-Tg-bovg-T22128-Ag-1/ GM-Tg-bovg-T22128-Ag-2 Bovine GAD65/GAD2 protein Bovine
GM-Tg-equg-T22128-Ag-1/ GM-Tg-equg-T22128-Ag-2 Equine GAD65/GAD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T22128-Ag-1/ GM-Tg-hg-T22128-Ag-2; GM-Tg-rg-T22128-Ag-1/ GM-Tg-rg-T22128-Ag-2;
GM-Tg-mg-T22128-Ag-1/ GM-Tg-mg-T22128-Ag-2; GM-Tg-cynog-T22128-Ag-1/ GM-Tg-cynog-T22128-Ag-2;
GM-Tg-felg-T22128-Ag-1/ GM-Tg-felg-T22128-Ag-2; GM-Tg-cang-T22128-Ag-1/ GM-Tg-cang-T22128-Ag-2;
GM-Tg-bovg-T22128-Ag-1/ GM-Tg-bovg-T22128-Ag-2; GM-Tg-equg-T22128-Ag-1/ GM-Tg-equg-T22128-Ag-2
Products Name GAD65/GAD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GAD65/GAD2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GAD65/GAD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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