Recombinant multi-species NOD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NOD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]
The Alternative Names of target: C230079P11,CARD4,CLR7.1,Card4,Caspase recruitment domain-containing protein 4,F830007N14Rik,NLRC1,NOD1,Nlrc1,Nod1,Nucleotide-binding oligomerization domain-containing protein 1,RGD1562269,hNod1,mNod1

Target products collectionGo to NOD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T21038-Ag-1/ GM-Tg-hg-T21038-Ag-2 Human NOD1 protein Human
GM-Tg-rg-T21038-Ag-1/ GM-Tg-rg-T21038-Ag-2 Rat NOD1 protein Rat
GM-Tg-mg-T21038-Ag-1/ GM-Tg-mg-T21038-Ag-2 Mouse NOD1 protein Mouse
GM-Tg-cynog-T21038-Ag-1/ GM-Tg-cynog-T21038-Ag-2 Cynomolgus/Rhesus macaque NOD1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T21038-Ag-1/ GM-Tg-felg-T21038-Ag-2 Feline NOD1 protein Feline
GM-Tg-cang-T21038-Ag-1/ GM-Tg-cang-T21038-Ag-2 Canine NOD1 protein Canine
GM-Tg-bovg-T21038-Ag-1/ GM-Tg-bovg-T21038-Ag-2 Bovine NOD1 protein Bovine
GM-Tg-equg-T21038-Ag-1/ GM-Tg-equg-T21038-Ag-2 Equine NOD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T21038-Ag-1/ GM-Tg-hg-T21038-Ag-2; GM-Tg-rg-T21038-Ag-1/ GM-Tg-rg-T21038-Ag-2;
GM-Tg-mg-T21038-Ag-1/ GM-Tg-mg-T21038-Ag-2; GM-Tg-cynog-T21038-Ag-1/ GM-Tg-cynog-T21038-Ag-2;
GM-Tg-felg-T21038-Ag-1/ GM-Tg-felg-T21038-Ag-2; GM-Tg-cang-T21038-Ag-1/ GM-Tg-cang-T21038-Ag-2;
GM-Tg-bovg-T21038-Ag-1/ GM-Tg-bovg-T21038-Ag-2; GM-Tg-equg-T21038-Ag-1/ GM-Tg-equg-T21038-Ag-2
Products Name NOD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NOD1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NOD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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