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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T21038
|
| Target Name |
NOD1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10392
|
| Gene ID |
100069844 (Equus caballus), 101086963 (Felis catus), 10392 (Homo sapiens), 107607 (Mus musculus) 482382 (Canis lupus familiaris), 500133 (Rattus norvegicus), 695655 (Macaca mulatta), 781426 (Bos taurus)
|
| Target Alternative Names |
C230079P11,CARD4,CLR7.1,Card4,Caspase recruitment domain-containing protein 4,F830007N14Rik,NLRC1,NOD1,Nlrc1,Nod1,Nucleotide-binding oligomerization domain-containing protein 1,RGD1562269,hNod1,mNod1
|
| Uniprot Accession |
Q9Y239,Q8BHB0
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
NOD-like receptor signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pertussis
|
| Gene Ensembl |
ENSECAG00000013825, ENSG00000106100, ENSMUSG00000038058, ENSCAFG00845019451, ENSMMUG00000012547, ENSBTAG00000038235
|
Pre-made viral vector of NOD1 cDNA Clones/ORF Plasmid
NOD1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10392 | Pre-made Human NOD1/CARD4/NLRC1 siRNA oligo Duplex | 10392 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500133 | Pre-made Rat Nod1/RGD1562269 siRNA oligo Duplex | 500133 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107607 | Pre-made Mouse Nod1/Card4/Nlrc1 siRNA oligo Duplex | 107607 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695655 | Pre-made Cynomolgus/Rhesus macaque NOD1/CARD4 siRNA oligo Duplex | 695655 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086963 | Pre-made Cat/Feline NOD1 siRNA oligo Duplex | 101086963 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482382 | Pre-made Dog/Canine NOD1 siRNA oligo Duplex | 482382 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo781426 | Pre-made Bovines/Cattle NOD1 siRNA oligo Duplex | 781426 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069844 | Pre-made Equine/Horse NOD1 siRNA oligo Duplex | 100069844 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NOD1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T21038-Ab | Human | Anti-Human NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T21038-Ab | Rat | Anti-Rat NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T21038-Ab | Mouse | Anti-Mouse NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T21038-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T21038-Ab | Cat/Feline | Anti-Cat/Feline NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T21038-Ab | Dog/Canine | Anti-Dog/Canine NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T21038-Ab | Bovines/Cattle | Anti-Bovines/Cattle NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T21038-Ab | Equine/Horse | Anti-Equine/Horse NOD1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
NOD1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T21038-Ag | Human | Human NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T21038-Ag | Rat | Rat NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T21038-Ag | Mouse | Mouse NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T21038-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T21038-Ag | Cat/Feline | Cat/Feline NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T21038-Ag | Dog/Canine | Dog/Canine NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T21038-Ag | Bovines/Cattle | Bovines/Cattle NOD1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T21038-Ag | Equine/Horse | Equine/Horse NOD1 recombinant protein | Mammalian cell | Detail |