Recombinant multi-species ALAD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALAD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
The Alternative Names of target: ALAD,ALADH,ALADR,Alad,Delta-aminolevulinic acid dehydratase,Lv,PBGS,Porphobilinogen synthase

Target products collectionGo to ALAD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T20514-Ag-1/ GM-Tg-hg-T20514-Ag-2 Human ALAD protein Human
GM-Tg-rg-T20514-Ag-1/ GM-Tg-rg-T20514-Ag-2 Rat ALAD protein Rat
GM-Tg-mg-T20514-Ag-1/ GM-Tg-mg-T20514-Ag-2 Mouse ALAD protein Mouse
GM-Tg-cynog-T20514-Ag-1/ GM-Tg-cynog-T20514-Ag-2 Cynomolgus/Rhesus macaque ALAD protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T20514-Ag-1/ GM-Tg-felg-T20514-Ag-2 Feline ALAD protein Feline
GM-Tg-cang-T20514-Ag-1/ GM-Tg-cang-T20514-Ag-2 Canine ALAD protein Canine
GM-Tg-bovg-T20514-Ag-1/ GM-Tg-bovg-T20514-Ag-2 Bovine ALAD protein Bovine
GM-Tg-equg-T20514-Ag-1/ GM-Tg-equg-T20514-Ag-2 Equine ALAD protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T20514-Ag-1/ GM-Tg-hg-T20514-Ag-2; GM-Tg-rg-T20514-Ag-1/ GM-Tg-rg-T20514-Ag-2;
GM-Tg-mg-T20514-Ag-1/ GM-Tg-mg-T20514-Ag-2; GM-Tg-cynog-T20514-Ag-1/ GM-Tg-cynog-T20514-Ag-2;
GM-Tg-felg-T20514-Ag-1/ GM-Tg-felg-T20514-Ag-2; GM-Tg-cang-T20514-Ag-1/ GM-Tg-cang-T20514-Ag-2;
GM-Tg-bovg-T20514-Ag-1/ GM-Tg-bovg-T20514-Ag-2; GM-Tg-equg-T20514-Ag-1/ GM-Tg-equg-T20514-Ag-2
Products Name ALAD protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ALAD
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALAD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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