Recombinant multi-species Cyclin E2/CCNE2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclin E2/CCNE2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CCNE2,CYCE2,Ccne2,Cyclin E2,G1/S-specific cyclin-E2

Target products collectionGo to Cyclin E2/CCNE2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T19027-Ag-1/ GM-Tg-hg-T19027-Ag-2 Human Cyclin E2/CCNE2 protein Human
GM-Tg-rg-T19027-Ag-1/ GM-Tg-rg-T19027-Ag-2 Rat Cyclin E2/CCNE2 protein Rat
GM-Tg-mg-T19027-Ag-1/ GM-Tg-mg-T19027-Ag-2 Mouse Cyclin E2/CCNE2 protein Mouse
GM-Tg-cynog-T19027-Ag-1/ GM-Tg-cynog-T19027-Ag-2 Cynomolgus/Rhesus macaque Cyclin E2/CCNE2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T19027-Ag-1/ GM-Tg-felg-T19027-Ag-2 Feline Cyclin E2/CCNE2 protein Feline
GM-Tg-cang-T19027-Ag-1/ GM-Tg-cang-T19027-Ag-2 Canine Cyclin E2/CCNE2 protein Canine
GM-Tg-bovg-T19027-Ag-1/ GM-Tg-bovg-T19027-Ag-2 Bovine Cyclin E2/CCNE2 protein Bovine
GM-Tg-equg-T19027-Ag-1/ GM-Tg-equg-T19027-Ag-2 Equine Cyclin E2/CCNE2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T19027-Ag-1/ GM-Tg-hg-T19027-Ag-2; GM-Tg-rg-T19027-Ag-1/ GM-Tg-rg-T19027-Ag-2;
GM-Tg-mg-T19027-Ag-1/ GM-Tg-mg-T19027-Ag-2; GM-Tg-cynog-T19027-Ag-1/ GM-Tg-cynog-T19027-Ag-2;
GM-Tg-felg-T19027-Ag-1/ GM-Tg-felg-T19027-Ag-2; GM-Tg-cang-T19027-Ag-1/ GM-Tg-cang-T19027-Ag-2;
GM-Tg-bovg-T19027-Ag-1/ GM-Tg-bovg-T19027-Ag-2; GM-Tg-equg-T19027-Ag-1/ GM-Tg-equg-T19027-Ag-2
Products Name Cyclin E2/CCNE2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cyclin E2/CCNE2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclin E2/CCNE2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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