Explore Cyclin E2/CCNE2 gene products and cross-species
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T19027
|
| Target Name |
Cyclin E2/CCNE2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9134
|
| Gene ID |
100055302 (Equus caballus), 101085347 (Felis catus), 12448 (Mus musculus), 362485 (Rattus norvegicus) 487057 (Canis lupus familiaris), 538436 (Bos taurus), 700382 (Macaca mulatta), 9134 (Homo sapiens)
|
| Target Alternative Names |
CCNE2,CYCE2,Ccne2,Cyclin E2,G1/S-specific cyclin-E2
|
| Uniprot Accession |
Q9Z238,Q5E9K7,O96020
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
p53 signaling pathway, PI3K-Akt signaling pathway, Cellular senescence, Cushing syndrome, Hepatitis B, Measles, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Pathways in cancer, Prostate cancer, Small cell lung cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000020270, ENSMUSG00000028212, ENSCAFG00845016153, ENSBTAG00000004906, ENSMMUG00000005358, ENSG00000175305
|
Pre-made viral vector of Cyclin E2/CCNE2 cDNA Clones/ORF Plasmid
Cyclin E2/CCNE2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9134 | Pre-made Human CCNE2/CYCE2 siRNA oligo Duplex | 9134 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362485 | Pre-made Rat Ccne2 siRNA oligo Duplex | 362485 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12448 | Pre-made Mouse Ccne2 siRNA oligo Duplex | 12448 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700382 | Pre-made Cynomolgus/Rhesus macaque CCNE2 siRNA oligo Duplex | 700382 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085347 | Pre-made Cat/Feline CCNE2 siRNA oligo Duplex | 101085347 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487057 | Pre-made Dog/Canine CCNE2 siRNA oligo Duplex | 487057 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538436 | Pre-made Bovines/Cattle CCNE2 siRNA oligo Duplex | 538436 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055302 | Pre-made Equine/Horse CCNE2 siRNA oligo Duplex | 100055302 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cyclin E2/CCNE2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T19027-Ab | Human | Anti-Human Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-T19027-Ab | Rat | Anti-Rat Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-T19027-Ab | Mouse | Anti-Mouse Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-T19027-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-T19027-Ab | Cat/Feline | Anti-Cat/Feline Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-T19027-Ab | Dog/Canine | Anti-Dog/Canine Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-T19027-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-T19027-Ab | Equine/Horse | Anti-Equine/Horse Cyclin E2/CCNE2 monoclonal antibody | mab | | Detail |
Cyclin E2/CCNE2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T19027-Ag | Human | Human Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T19027-Ag | Rat | Rat Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T19027-Ag | Mouse | Mouse Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T19027-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T19027-Ag | Cat/Feline | Cat/Feline Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T19027-Ag | Dog/Canine | Dog/Canine Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T19027-Ag | Bovines/Cattle | Bovines/Cattle Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T19027-Ag | Equine/Horse | Equine/Horse Cyclin E2/CCNE2 recombinant protein | Mammalian cell | Detail |