Recombinant multi-species FGF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
The Alternative Names of target: AFGF,Acidic fibroblast growth factor (aFGF),Dffrx,ECGF,ECGF-beta,ECGFA,ECGFB,EDGF,EDGF II,Endothelial cell growth factor (ECGF),FGF-1,FGF-alpha,FGF1,FGF2B,FGFA,Fam,Fgf-1,Fgf1,Fgf2b,Fgfa,Fibroblast growth factor 1,GLIO703,HBGF-1,HBGF1,Heparin-binding growth factor 1 (HBGF-1),aFGF

Target products collectionGo to FGF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T18639-Ag-1/ GM-Tg-hg-T18639-Ag-2 Human FGF1 protein Human
GM-Tg-rg-T18639-Ag-1/ GM-Tg-rg-T18639-Ag-2 Rat FGF1 protein Rat
GM-Tg-mg-T18639-Ag-1/ GM-Tg-mg-T18639-Ag-2 Mouse FGF1 protein Mouse
GM-Tg-cynog-T18639-Ag-1/ GM-Tg-cynog-T18639-Ag-2 Cynomolgus/Rhesus macaque FGF1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T18639-Ag-1/ GM-Tg-felg-T18639-Ag-2 Feline FGF1 protein Feline
GM-Tg-cang-T18639-Ag-1/ GM-Tg-cang-T18639-Ag-2 Canine FGF1 protein Canine
GM-Tg-bovg-T18639-Ag-1/ GM-Tg-bovg-T18639-Ag-2 Bovine FGF1 protein Bovine
GM-Tg-equg-T18639-Ag-1/ GM-Tg-equg-T18639-Ag-2 Equine FGF1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T18639-Ag-1/ GM-Tg-hg-T18639-Ag-2; GM-Tg-rg-T18639-Ag-1/ GM-Tg-rg-T18639-Ag-2;
GM-Tg-mg-T18639-Ag-1/ GM-Tg-mg-T18639-Ag-2; GM-Tg-cynog-T18639-Ag-1/ GM-Tg-cynog-T18639-Ag-2;
GM-Tg-felg-T18639-Ag-1/ GM-Tg-felg-T18639-Ag-2; GM-Tg-cang-T18639-Ag-1/ GM-Tg-cang-T18639-Ag-2;
GM-Tg-bovg-T18639-Ag-1/ GM-Tg-bovg-T18639-Ag-2; GM-Tg-equg-T18639-Ag-1/ GM-Tg-equg-T18639-Ag-2
Products Name FGF1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FGF1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.