Explore FGF1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
| Target ID |
GM-T18639
|
| Target Name |
FGF1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2246
|
| Gene ID |
100033960 (Equus caballus), 101082206 (Felis catus), 14164 (Mus musculus), 2246 (Homo sapiens)
25317 (Rattus norvegicus), 281160 (Bos taurus), 607724 (Canis lupus familiaris), 705970 (Macaca mulatta)
|
| Target Alternative Names |
AFGF,Acidic fibroblast growth factor (aFGF),Dffrx,ECGF,ECGF-beta,ECGFA,ECGFB,EDGF,EDGF II,Endothelial cell growth factor (ECGF),FGF-1,FGF-alpha,FGF1,FGF2B,FGFA,Fam,Fgf-1,Fgf1,Fgf2b,Fgfa,Fibroblast growth factor 1,GLIO703,HBGF-1,HBGF1,Heparin-binding growth factor 1 (HBGF-1),aFGF
|
| Uniprot Accession |
P61148,P05230,P61149,P03968,P18651
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Hippo signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000020769, ENSMUSG00000036585, ENSG00000113578, ENSBTAG00000005198, ENSCAFG00845017942, ENSMMUG00000057828
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of FGF1 cDNA Clones/ORF Plasmid
FGF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2246 | Pre-made Human FGF1/AFGF/ECGF siRNA oligo Duplex | 2246 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25317 | Pre-made Rat Fgf1/FGF-1/Fgf2b siRNA oligo Duplex | 25317 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14164 | Pre-made Mouse Fgf1/Fam/Fgfa siRNA oligo Duplex | 14164 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705970 | Pre-made Cynomolgus/Rhesus macaque FGF1 siRNA oligo Duplex | 705970 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082206 | Pre-made Cat/Feline FGF1 siRNA oligo Duplex | 101082206 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607724 | Pre-made Dog/Canine FGF1/ECGF/aFGF siRNA oligo Duplex | 607724 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281160 | Pre-made Bovines/Cattle FGF1/ECGF/EDGF siRNA oligo Duplex | 281160 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033960 | Pre-made Equine/Horse FGF1/FGF2B siRNA oligo Duplex | 100033960 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T18639-Ab | Human | Anti-Human FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T18639-Ab | Rat | Anti-Rat FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T18639-Ab | Mouse | Anti-Mouse FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T18639-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T18639-Ab | Cat/Feline | Anti-Cat/Feline FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T18639-Ab | Dog/Canine | Anti-Dog/Canine FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T18639-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T18639-Ab | Equine/Horse | Anti-Equine/Horse FGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
FGF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T18639-Ag | Human | Human FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T18639-Ag | Rat | Rat FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T18639-Ag | Mouse | Mouse FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T18639-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T18639-Ag | Cat/Feline | Cat/Feline FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T18639-Ag | Dog/Canine | Dog/Canine FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T18639-Ag | Bovines/Cattle | Bovines/Cattle FGF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T18639-Ag | Equine/Horse | Equine/Horse FGF1 recombinant protein | Mammalian cell | Detail |
