Recombinant multi-species P62/SQSTM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine P62/SQSTM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
The Alternative Names of target: A170,DMRV,EBI3-associated protein of 60 kDa (EBIAP,EBIAP,FTDALS3,NADGP,OSF-6,OSIL,Osi,P62,PDB3,Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa,SQSTM1,STAP,STONE14,Sequestosome-1,Sqstm1,Ubiquitin-binding protein p62 (p62),ZIP,ZIP3,p60,p60),p62,p62B

Target products collectionGo to P62/SQSTM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T17367-Ag-1/ GM-Tg-hg-T17367-Ag-2 Human P62/SQSTM1 protein Human
GM-Tg-rg-T17367-Ag-1/ GM-Tg-rg-T17367-Ag-2 Rat P62/SQSTM1 protein Rat
GM-Tg-mg-T17367-Ag-1/ GM-Tg-mg-T17367-Ag-2 Mouse P62/SQSTM1 protein Mouse
GM-Tg-cynog-T17367-Ag-1/ GM-Tg-cynog-T17367-Ag-2 Cynomolgus/Rhesus macaque P62/SQSTM1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T17367-Ag-1/ GM-Tg-felg-T17367-Ag-2 Feline P62/SQSTM1 protein Feline
GM-Tg-cang-T17367-Ag-1/ GM-Tg-cang-T17367-Ag-2 Canine P62/SQSTM1 protein Canine
GM-Tg-bovg-T17367-Ag-1/ GM-Tg-bovg-T17367-Ag-2 Bovine P62/SQSTM1 protein Bovine
GM-Tg-equg-T17367-Ag-1/ GM-Tg-equg-T17367-Ag-2 Equine P62/SQSTM1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T17367-Ag-1/ GM-Tg-hg-T17367-Ag-2; GM-Tg-rg-T17367-Ag-1/ GM-Tg-rg-T17367-Ag-2;
GM-Tg-mg-T17367-Ag-1/ GM-Tg-mg-T17367-Ag-2; GM-Tg-cynog-T17367-Ag-1/ GM-Tg-cynog-T17367-Ag-2;
GM-Tg-felg-T17367-Ag-1/ GM-Tg-felg-T17367-Ag-2; GM-Tg-cang-T17367-Ag-1/ GM-Tg-cang-T17367-Ag-2;
GM-Tg-bovg-T17367-Ag-1/ GM-Tg-bovg-T17367-Ag-2; GM-Tg-equg-T17367-Ag-1/ GM-Tg-equg-T17367-Ag-2
Products Name P62/SQSTM1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name P62/SQSTM1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine P62/SQSTM1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.