Recombinant multi-species MEK5/MAP2K5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MEK5/MAP2K5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
The Alternative Names of target: Dual specificity mitogen-activated protein kinase kinase 5,HsT17454,MAP kinase kinase 5,MAP2K5,MAPK/ERK kinase 5 (MEK 5),MAPKK 5,MAPKK5,MEK5,Map2k5,Mapkk5,Mek5,PRKMK5,Prkmk5
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T17143-Ag-1/ GM-Tg-hg-T17143-Ag-2 | Human MEK5/MAP2K5 protein | Human |
| GM-Tg-rg-T17143-Ag-1/ GM-Tg-rg-T17143-Ag-2 | Rat MEK5/MAP2K5 protein | Rat |
| GM-Tg-mg-T17143-Ag-1/ GM-Tg-mg-T17143-Ag-2 | Mouse MEK5/MAP2K5 protein | Mouse |
| GM-Tg-cynog-T17143-Ag-1/ GM-Tg-cynog-T17143-Ag-2 | Cynomolgus/Rhesus macaque MEK5/MAP2K5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T17143-Ag-1/ GM-Tg-felg-T17143-Ag-2 | Feline MEK5/MAP2K5 protein | Feline |
| GM-Tg-cang-T17143-Ag-1/ GM-Tg-cang-T17143-Ag-2 | Canine MEK5/MAP2K5 protein | Canine |
| GM-Tg-bovg-T17143-Ag-1/ GM-Tg-bovg-T17143-Ag-2 | Bovine MEK5/MAP2K5 protein | Bovine |
| GM-Tg-equg-T17143-Ag-1/ GM-Tg-equg-T17143-Ag-2 | Equine MEK5/MAP2K5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T17143-Ag-1/ GM-Tg-hg-T17143-Ag-2;
GM-Tg-rg-T17143-Ag-1/ GM-Tg-rg-T17143-Ag-2;
GM-Tg-mg-T17143-Ag-1/ GM-Tg-mg-T17143-Ag-2; GM-Tg-cynog-T17143-Ag-1/ GM-Tg-cynog-T17143-Ag-2; GM-Tg-felg-T17143-Ag-1/ GM-Tg-felg-T17143-Ag-2; GM-Tg-cang-T17143-Ag-1/ GM-Tg-cang-T17143-Ag-2; GM-Tg-bovg-T17143-Ag-1/ GM-Tg-bovg-T17143-Ag-2; GM-Tg-equg-T17143-Ag-1/ GM-Tg-equg-T17143-Ag-2 |
| Products Name | MEK5/MAP2K5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | MEK5/MAP2K5 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MEK5/MAP2K5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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Through
expression in mammalian cell lines, GMab has
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reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.