Recombinant multi-species PCAF/KAT2B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCAF/KAT2B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
The Alternative Names of target: A930006P13Rik,AABR07066180.1,CAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF (Histone acetylase PCAF),KAT2B,Kat2b,Lysine acetyltransferase 2B,P/CAF,P300/CBP-associated factor (P/CAF),PCAF,Pcaf,Spermidine acetyltransferase KAT2B,p/CAF
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T16902-Ag-1/ GM-Tg-hg-T16902-Ag-2 | Human PCAF/KAT2B protein | Human |
| GM-Tg-rg-T16902-Ag-1/ GM-Tg-rg-T16902-Ag-2 | Rat PCAF/KAT2B protein | Rat |
| GM-Tg-mg-T16902-Ag-1/ GM-Tg-mg-T16902-Ag-2 | Mouse PCAF/KAT2B protein | Mouse |
| GM-Tg-cynog-T16902-Ag-1/ GM-Tg-cynog-T16902-Ag-2 | Cynomolgus/Rhesus macaque PCAF/KAT2B protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T16902-Ag-1/ GM-Tg-felg-T16902-Ag-2 | Feline PCAF/KAT2B protein | Feline |
| GM-Tg-cang-T16902-Ag-1/ GM-Tg-cang-T16902-Ag-2 | Canine PCAF/KAT2B protein | Canine |
| GM-Tg-bovg-T16902-Ag-1/ GM-Tg-bovg-T16902-Ag-2 | Bovine PCAF/KAT2B protein | Bovine |
| GM-Tg-equg-T16902-Ag-1/ GM-Tg-equg-T16902-Ag-2 | Equine PCAF/KAT2B protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T16902-Ag-1/ GM-Tg-hg-T16902-Ag-2;
GM-Tg-rg-T16902-Ag-1/ GM-Tg-rg-T16902-Ag-2;
GM-Tg-mg-T16902-Ag-1/ GM-Tg-mg-T16902-Ag-2; GM-Tg-cynog-T16902-Ag-1/ GM-Tg-cynog-T16902-Ag-2; GM-Tg-felg-T16902-Ag-1/ GM-Tg-felg-T16902-Ag-2; GM-Tg-cang-T16902-Ag-1/ GM-Tg-cang-T16902-Ag-2; GM-Tg-bovg-T16902-Ag-1/ GM-Tg-bovg-T16902-Ag-2; GM-Tg-equg-T16902-Ag-1/ GM-Tg-equg-T16902-Ag-2 |
| Products Name | PCAF/KAT2B protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PCAF/KAT2B |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCAF/KAT2B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.