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Target
sublocation: Introcelluar Protein.
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T16902
|
| Target Name |
PCAF/KAT2B
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8850
|
| Gene ID |
100061976 (Equus caballus), 101080732 (Felis catus), 18519 (Mus musculus), 301164 (Rattus norvegicus) 407215 (Bos taurus), 477052 (Canis lupus familiaris), 698283 (Macaca mulatta), 8850 (Homo sapiens)
|
| Target Alternative Names |
A930006P13Rik,AABR07066180.1,CAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF (Histone acetylase PCAF),KAT2B,Kat2b,Lysine acetyltransferase 2B,P/CAF,P300/CBP-associated factor (P/CAF),PCAF,Pcaf,Spermidine acetyltransferase KAT2B,p/CAF
|
| Uniprot Accession |
Q9JHD1,Q92831
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Thyroid hormone signaling pathway, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000013925, ENSMUSG00000000708, ENSBTAG00000000746, ENSCAFG00845020587, ENSMMUG00000020342, ENSG00000114166
|
PCAF/KAT2B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8850 | Pre-made Human KAT2B/CAF/PCAF siRNA oligo Duplex | 8850 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301164 | Pre-made Rat Kat2b/Pcaf/AABR07066180.1 siRNA oligo Duplex | 301164 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18519 | Pre-made Mouse Kat2b/Pcaf/p/CAF siRNA oligo Duplex | 18519 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698283 | Pre-made Cynomolgus/Rhesus macaque KAT2B siRNA oligo Duplex | 698283 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080732 | Pre-made Cat/Feline KAT2B siRNA oligo Duplex | 101080732 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477052 | Pre-made Dog/Canine KAT2B/PCAF siRNA oligo Duplex | 477052 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407215 | Pre-made Bovines/Cattle KAT2B/PCAF siRNA oligo Duplex | 407215 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061976 | Pre-made Equine/Horse KAT2B/PCAF siRNA oligo Duplex | 100061976 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PCAF/KAT2B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16902-Ab | Human | Anti-Human PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16902-Ab | Rat | Anti-Rat PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16902-Ab | Mouse | Anti-Mouse PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16902-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16902-Ab | Cat/Feline | Anti-Cat/Feline PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16902-Ab | Dog/Canine | Anti-Dog/Canine PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16902-Ab | Bovines/Cattle | Anti-Bovines/Cattle PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16902-Ab | Equine/Horse | Anti-Equine/Horse PCAF/KAT2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PCAF/KAT2B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16902-Ag | Human | Human PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T16902-Ag | Rat | Rat PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T16902-Ag | Mouse | Mouse PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T16902-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T16902-Ag | Cat/Feline | Cat/Feline PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T16902-Ag | Dog/Canine | Dog/Canine PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T16902-Ag | Bovines/Cattle | Bovines/Cattle PCAF/KAT2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T16902-Ag | Equine/Horse | Equine/Horse PCAF/KAT2B recombinant protein | Mammalian cell | Detail |