Recombinant multi-species RANTES/CCL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RANTES/CCL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
The Alternative Names of target: C-C motif chemokine 5,CCL5,Ccl5,D17S136E,EoCP,Eosinophil chemotactic cytokine,MuRantes,RANTES,Rantes,SCYA5,SIS-delta,SISd,Scya5,Small-inducible cytokine A5,T cell-specific protein P228 (TCP228),T-cell-specific protein RANTES,TCP228,eoCP

Target products collectionGo to RANTES/CCL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T16263-Ag-1/ GM-Tg-hg-T16263-Ag-2 Human RANTES/CCL5 protein Human
GM-Tg-rg-T16263-Ag-1/ GM-Tg-rg-T16263-Ag-2 Rat RANTES/CCL5 protein Rat
GM-Tg-mg-T16263-Ag-1/ GM-Tg-mg-T16263-Ag-2 Mouse RANTES/CCL5 protein Mouse
GM-Tg-cynog-T16263-Ag-1/ GM-Tg-cynog-T16263-Ag-2 Cynomolgus/Rhesus macaque RANTES/CCL5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T16263-Ag-1/ GM-Tg-felg-T16263-Ag-2 Feline RANTES/CCL5 protein Feline
GM-Tg-cang-T16263-Ag-1/ GM-Tg-cang-T16263-Ag-2 Canine RANTES/CCL5 protein Canine
GM-Tg-bovg-T16263-Ag-1/ GM-Tg-bovg-T16263-Ag-2 Bovine RANTES/CCL5 protein Bovine
GM-Tg-equg-T16263-Ag-1/ GM-Tg-equg-T16263-Ag-2 Equine RANTES/CCL5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T16263-Ag-1/ GM-Tg-hg-T16263-Ag-2; GM-Tg-rg-T16263-Ag-1/ GM-Tg-rg-T16263-Ag-2;
GM-Tg-mg-T16263-Ag-1/ GM-Tg-mg-T16263-Ag-2; GM-Tg-cynog-T16263-Ag-1/ GM-Tg-cynog-T16263-Ag-2;
GM-Tg-felg-T16263-Ag-1/ GM-Tg-felg-T16263-Ag-2; GM-Tg-cang-T16263-Ag-1/ GM-Tg-cang-T16263-Ag-2;
GM-Tg-bovg-T16263-Ag-1/ GM-Tg-bovg-T16263-Ag-2; GM-Tg-equg-T16263-Ag-1/ GM-Tg-equg-T16263-Ag-2
Products Name RANTES/CCL5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RANTES/CCL5
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RANTES/CCL5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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