Recombinant multi-species ALOX15/15-LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOX15/15-LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
The Alternative Names of target: ALOX15, 15-LOX,Polyunsaturated fatty acid lipoxygenase ALOX15,12/15-lipoxygenase, Arachidonate 12-lipoxygenase, leukocyte-type (12-LOX), Arachidonate 15-lipoxygenase (15-LOX, 15-LOX-1), Arachidonate omega-6 lipoxygenase, Hepoxilin A3 synthase Alox15, Linoleate 13S-lipoxygenase,LOG15,12-LOX,15-LOX,15-LOX-1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T16042-Ab-1/ GM-Tg-hg-T16042-Ab-2 | Human ALOX15/15-LOX protein | Human |
GM-Tg-rg-T16042-Ab-1/ GM-Tg-rg-T16042-Ab-2 | Rat ALOX15/15-LOX protein | Rat |
GM-Tg-mg-T16042-Ab-1/ GM-Tg-mg-T16042-Ab-2 | Mouse ALOX15/15-LOX protein | Mouse |
GM-Tg-cynog-T16042-Ab-1/ GM-Tg-cynog-T16042-Ab-2 | Cynomolgus/Rhesus macaque ALOX15/15-LOX monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T16042-Ab-1/ GM-Tg-felg-T16042-Ab-2 | Feline ALOX15/15-LOX protein | Feline |
GM-Tg-cang-T16042-Ab-1/ GM-Tg-cang-T16042-Ab-2 | Canine ALOX15/15-LOX protein | Canine |
GM-Tg-bovg-T16042-Ab-1/ GM-Tg-bovg-T16042-Ab-2 | Bovine ALOX15/15-LOX protein | Bovine |
GM-Tg-equg-T16042-Ab-1/ GM-Tg-equg-T16042-Ab-2 | Equine ALOX15/15-LOX protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T16042-Ab-1/ GM-Tg-hg-T16042-Ab-2;
GM-Tg-rg-T16042-Ab-1/ GM-Tg-rg-T16042-Ab-2;
GM-Tg-mg-T16042-Ab-1/ GM-Tg-mg-T16042-Ab-2; GM-Tg-cynog-T16042-Ab-1/ GM-Tg-cynog-T16042-Ab-2; GM-Tg-felg-T16042-Ab-1/ GM-Tg-felg-T16042-Ab-2; GM-Tg-cang-T16042-Ab-1/ GM-Tg-cang-T16042-Ab-2; GM-Tg-bovg-T16042-Ab-1/ GM-Tg-bovg-T16042-Ab-2; GM-Tg-equg-T16042-Ab-1/ GM-Tg-equg-T16042-Ab-2 |
Products Name | ALOX15/15-LOX protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | ALOX15/15-LOX |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOX15/15-LOX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.