Recombinant multi-species ALOX15/15-LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOX15/15-LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
The Alternative Names of target: ALOX15, 15-LOX,Polyunsaturated fatty acid lipoxygenase ALOX15,12/15-lipoxygenase, Arachidonate 12-lipoxygenase, leukocyte-type (12-LOX), Arachidonate 15-lipoxygenase (15-LOX, 15-LOX-1), Arachidonate omega-6 lipoxygenase, Hepoxilin A3 synthase Alox15, Linoleate 13S-lipoxygenase,LOG15,12-LOX,15-LOX,15-LOX-1

Target products collectionGo to ALOX15/15-LOX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T16042-Ab-1/ GM-Tg-hg-T16042-Ab-2 Human ALOX15/15-LOX protein Human
GM-Tg-rg-T16042-Ab-1/ GM-Tg-rg-T16042-Ab-2 Rat ALOX15/15-LOX protein Rat
GM-Tg-mg-T16042-Ab-1/ GM-Tg-mg-T16042-Ab-2 Mouse ALOX15/15-LOX protein Mouse
GM-Tg-cynog-T16042-Ab-1/ GM-Tg-cynog-T16042-Ab-2 Cynomolgus/Rhesus macaque ALOX15/15-LOX monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T16042-Ab-1/ GM-Tg-felg-T16042-Ab-2 Feline ALOX15/15-LOX protein Feline
GM-Tg-cang-T16042-Ab-1/ GM-Tg-cang-T16042-Ab-2 Canine ALOX15/15-LOX protein Canine
GM-Tg-bovg-T16042-Ab-1/ GM-Tg-bovg-T16042-Ab-2 Bovine ALOX15/15-LOX protein Bovine
GM-Tg-equg-T16042-Ab-1/ GM-Tg-equg-T16042-Ab-2 Equine ALOX15/15-LOX protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T16042-Ab-1/ GM-Tg-hg-T16042-Ab-2; GM-Tg-rg-T16042-Ab-1/ GM-Tg-rg-T16042-Ab-2;
GM-Tg-mg-T16042-Ab-1/ GM-Tg-mg-T16042-Ab-2; GM-Tg-cynog-T16042-Ab-1/ GM-Tg-cynog-T16042-Ab-2;
GM-Tg-felg-T16042-Ab-1/ GM-Tg-felg-T16042-Ab-2; GM-Tg-cang-T16042-Ab-1/ GM-Tg-cang-T16042-Ab-2;
GM-Tg-bovg-T16042-Ab-1/ GM-Tg-bovg-T16042-Ab-2; GM-Tg-equg-T16042-Ab-1/ GM-Tg-equg-T16042-Ab-2
Products Name ALOX15/15-LOX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ALOX15/15-LOX
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALOX15/15-LOX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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