Explore ALOX15/15-LOX gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T16042
|
| Target Name |
ALOX15/15-LOX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
246
|
| Gene ID |
100072900 (Equus caballus), 246 (Homo sapiens), 709212 (Macaca mulatta)
|
| Target Alternative Names |
ALOX15,LOG15,12-LOX,15-LOX,15-LOX-1
|
| Uniprot Accession |
P16050
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Ferroptosis, Serotonergic synapse, Arachidonic acid metabolism, Linoleic acid metabolism
|
| Gene Ensembl |
ENSECAG00000038698, ENSG00000161905, ENSMMUG00000030381
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ALOX15/15-LOX cDNA Clones/ORF Plasmid
ALOX15/15-LOX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo246 | Pre-made Human ALOX15/LOG15/12-LOX siRNA oligo Duplex | 246 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709212 | Pre-made Cynomolgus/Rhesus macaque ALOX15 siRNA oligo Duplex | 709212 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072900 | Pre-made Equine/Horse ALOX15 siRNA oligo Duplex | 100072900 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ALOX15/15-LOX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16042-Ab | Human | Anti-Human ALOX15/15-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16042-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ALOX15/15-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16042-Ab | Equine/Horse | Anti-Equine/Horse ALOX15/15-LOX monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ALOX15/15-LOX recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16042-Ag | Human | Human ALOX15/15-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T16042-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ALOX15/15-LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T16042-Ag | Equine/Horse | Equine/Horse ALOX15/15-LOX recombinant protein | Mammalian cell | Detail |
