Recombinant multi-species UMPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UMPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
The Alternative Names of target: 1700095D23Rik,OPRT,UMP synthase,UMPS,Umps,Uridine 5'-monophosphate synthase

Target products collectionGo to UMPS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T15851-Ag-1/ GM-Tg-hg-T15851-Ag-2 Human UMPS protein Human
GM-Tg-rg-T15851-Ag-1/ GM-Tg-rg-T15851-Ag-2 Rat UMPS protein Rat
GM-Tg-mg-T15851-Ag-1/ GM-Tg-mg-T15851-Ag-2 Mouse UMPS protein Mouse
GM-Tg-cynog-T15851-Ag-1/ GM-Tg-cynog-T15851-Ag-2 Cynomolgus/Rhesus macaque UMPS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T15851-Ag-1/ GM-Tg-felg-T15851-Ag-2 Feline UMPS protein Feline
GM-Tg-cang-T15851-Ag-1/ GM-Tg-cang-T15851-Ag-2 Canine UMPS protein Canine
GM-Tg-bovg-T15851-Ag-1/ GM-Tg-bovg-T15851-Ag-2 Bovine UMPS protein Bovine
GM-Tg-equg-T15851-Ag-1/ GM-Tg-equg-T15851-Ag-2 Equine UMPS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T15851-Ag-1/ GM-Tg-hg-T15851-Ag-2; GM-Tg-rg-T15851-Ag-1/ GM-Tg-rg-T15851-Ag-2;
GM-Tg-mg-T15851-Ag-1/ GM-Tg-mg-T15851-Ag-2; GM-Tg-cynog-T15851-Ag-1/ GM-Tg-cynog-T15851-Ag-2;
GM-Tg-felg-T15851-Ag-1/ GM-Tg-felg-T15851-Ag-2; GM-Tg-cang-T15851-Ag-1/ GM-Tg-cang-T15851-Ag-2;
GM-Tg-bovg-T15851-Ag-1/ GM-Tg-bovg-T15851-Ag-2; GM-Tg-equg-T15851-Ag-1/ GM-Tg-equg-T15851-Ag-2
Products Name UMPS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name UMPS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UMPS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.