Explore UMPS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
| Target ID |
GM-T15851
|
| Target Name |
UMPS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7372
|
| Gene ID |
100070386 (Equus caballus), 101095364 (Felis catus), 22247 (Mus musculus), 281568 (Bos taurus)
288051 (Rattus norvegicus), 478593 (Canis lupus familiaris), 715664 (Macaca mulatta), 7372 (Homo sapiens)
|
| Target Alternative Names |
1700095D23Rik,OPRT,UMP synthase,UMPS,Umps,Uridine 5'-monophosphate synthase
|
| Uniprot Accession |
P13439,P31754,P11172
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000009708, ENSMUSG00000022814, ENSBTAG00000013727, ENSCAFG00845026912, ENSMMUG00000032009, ENSG00000114491
|
Pre-made viral vector of UMPS cDNA Clones/ORF Plasmid
UMPS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7372 | Pre-made Human UMPS/OPRT siRNA oligo Duplex | 7372 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo288051 | Pre-made Rat Umps siRNA oligo Duplex | 288051 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22247 | Pre-made Mouse Umps/1700095D23Rik siRNA oligo Duplex | 22247 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715664 | Pre-made Cynomolgus/Rhesus macaque UMPS siRNA oligo Duplex | 715664 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095364 | Pre-made Cat/Feline UMPS siRNA oligo Duplex | 101095364 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478593 | Pre-made Dog/Canine UMPS siRNA oligo Duplex | 478593 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281568 | Pre-made Bovines/Cattle UMPS siRNA oligo Duplex | 281568 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070386 | Pre-made Equine/Horse UMPS siRNA oligo Duplex | 100070386 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
UMPS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15851-Ab | Human | Anti-Human UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15851-Ab | Rat | Anti-Rat UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15851-Ab | Mouse | Anti-Mouse UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15851-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15851-Ab | Cat/Feline | Anti-Cat/Feline UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15851-Ab | Dog/Canine | Anti-Dog/Canine UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15851-Ab | Bovines/Cattle | Anti-Bovines/Cattle UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15851-Ab | Equine/Horse | Anti-Equine/Horse UMPS monoclonal antibody | mab | Therapeutics Target antibody | Detail |
UMPS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15851-Ag | Human | Human UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T15851-Ag | Rat | Rat UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T15851-Ag | Mouse | Mouse UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T15851-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T15851-Ag | Cat/Feline | Cat/Feline UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T15851-Ag | Dog/Canine | Dog/Canine UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T15851-Ag | Bovines/Cattle | Bovines/Cattle UMPS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T15851-Ag | Equine/Horse | Equine/Horse UMPS recombinant protein | Mammalian cell | Detail |
