Recombinant multi-species CDK11B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK11B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
The Alternative Names of target: CDC2L1,CDC2L2,CDK11,CDK11-p110,CDK11-p46,CDK11-p58,CDK11A,CDK11B,CLK-1,Cdc11b,Cdc2l1,Cdc2l2,Cdk11,Cdk11b,Cell division cycle 2-like protein kinase 1 (CLK-1),Cell division protein kinase 11B,Cyclin-dependent kinase 11B,Galactosyltransferase-associated protein kinase p58/GTA,PITSLRE serine/threonine-protein kinase CDC2L1,PITSLREA,PK58,p58,p58 CLK-1,p58CDC2L1,p58CLK-1

Target products collectionGo to CDK11B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T15722-Ag-1/ GM-Tg-hg-T15722-Ag-2 Human CDK11B protein Human
GM-Tg-rg-T15722-Ag-1/ GM-Tg-rg-T15722-Ag-2 Rat CDK11B protein Rat
GM-Tg-mg-T15722-Ag-1/ GM-Tg-mg-T15722-Ag-2 Mouse CDK11B protein Mouse
GM-Tg-cynog-T15722-Ag-1/ GM-Tg-cynog-T15722-Ag-2 Cynomolgus/Rhesus macaque CDK11B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T15722-Ag-1/ GM-Tg-felg-T15722-Ag-2 Feline CDK11B protein Feline
GM-Tg-cang-T15722-Ag-1/ GM-Tg-cang-T15722-Ag-2 Canine CDK11B protein Canine
GM-Tg-bovg-T15722-Ag-1/ GM-Tg-bovg-T15722-Ag-2 Bovine CDK11B protein Bovine
GM-Tg-equg-T15722-Ag-1/ GM-Tg-equg-T15722-Ag-2 Equine CDK11B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T15722-Ag-1/ GM-Tg-hg-T15722-Ag-2; GM-Tg-rg-T15722-Ag-1/ GM-Tg-rg-T15722-Ag-2;
GM-Tg-mg-T15722-Ag-1/ GM-Tg-mg-T15722-Ag-2; GM-Tg-cynog-T15722-Ag-1/ GM-Tg-cynog-T15722-Ag-2;
GM-Tg-felg-T15722-Ag-1/ GM-Tg-felg-T15722-Ag-2; GM-Tg-cang-T15722-Ag-1/ GM-Tg-cang-T15722-Ag-2;
GM-Tg-bovg-T15722-Ag-1/ GM-Tg-bovg-T15722-Ag-2; GM-Tg-equg-T15722-Ag-1/ GM-Tg-equg-T15722-Ag-2
Products Name CDK11B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDK11B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK11B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.