Explore CDK11B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
| Target ID |
GM-T15722
|
| Target Name |
CDK11B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
984
|
| Gene ID |
100033941 (Equus caballus), 12537 (Mus musculus), 252879 (Rattus norvegicus), 493708 (Bos taurus)
703046 (Macaca mulatta), 984 (Homo sapiens)
|
| Target Alternative Names |
CDC2L1,CDC2L2,CDK11,CDK11-p110,CDK11-p46,CDK11-p58,CDK11A,CDK11B,CLK-1,Cdc11b,Cdc2l1,Cdc2l2,Cdk11,Cdk11b,Cell division cycle 2-like protein kinase 1 (CLK-1),Cell division protein kinase 11B,Cyclin-dependent kinase 11B,Galactosyltransferase-associated protein kinase p58/GTA,PITSLRE serine/threonine-protein kinase CDC2L1,PITSLREA,PK58,p58,p58 CLK-1,p58CDC2L1,p58CLK-1
|
| Uniprot Accession |
P24788,P46892,P21127
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000002115, ENSMUSG00000029062, ENSBTAG00000010737, ENSMMUG00000001894, ENSG00000248333
|
| Target Classification |
Kinase
|
CDK11B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo984 | Pre-made Human CDK11B/p58/PK58 siRNA oligo Duplex | 984 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo252879 | Pre-made Rat Cdk11b/Cdk11/Cdc2l1 siRNA oligo Duplex | 252879 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12537 | Pre-made Mouse Cdk11b/p58/Cdk11 siRNA oligo Duplex | 12537 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703046 | Pre-made Cynomolgus/Rhesus macaque CDK11B/CDC2L1/CDK11A siRNA oligo Duplex | 703046 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493708 | Pre-made Bovines/Cattle CDK11B/CDK11/CDC2L1 siRNA oligo Duplex | 493708 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033941 | Pre-made Equine/Horse CDK11/CDC2L2/CDK11A siRNA oligo Duplex | 100033941 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CDK11B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15722-Ab | Human | Anti-Human CDK11B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15722-Ab | Rat | Anti-Rat CDK11B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15722-Ab | Mouse | Anti-Mouse CDK11B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15722-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CDK11B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15722-Ab | Bovines/Cattle | Anti-Bovines/Cattle CDK11B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15722-Ab | Equine/Horse | Anti-Equine/Horse CDK11B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CDK11B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15722-Ag | Human | Human CDK11B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T15722-Ag | Rat | Rat CDK11B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T15722-Ag | Mouse | Mouse CDK11B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T15722-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CDK11B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T15722-Ag | Bovines/Cattle | Bovines/Cattle CDK11B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T15722-Ag | Equine/Horse | Equine/Horse CDK11B recombinant protein | Mammalian cell | Detail |
