Recombinant multi-species FAK/PTK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FAK/PTK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
The Alternative Names of target: FADK,FADK 1,FAK,FAK1,FRNK,Fadk,Focal adhesion kinase 1,Focal adhesion kinase-related nonkinase (FRNK),PPP1R71,PTK2,Protein phosphatase 1 regulatory subunit 71 (PPP1R71),Protein-tyrosine kinase 2,Ptk2,p125FAK,pp125FAK

Target products collectionGo to FAK/PTK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T15068-Ag-1/ GM-Tg-hg-T15068-Ag-2 Human FAK/PTK2 protein Human
GM-Tg-rg-T15068-Ag-1/ GM-Tg-rg-T15068-Ag-2 Rat FAK/PTK2 protein Rat
GM-Tg-mg-T15068-Ag-1/ GM-Tg-mg-T15068-Ag-2 Mouse FAK/PTK2 protein Mouse
GM-Tg-cynog-T15068-Ag-1/ GM-Tg-cynog-T15068-Ag-2 Cynomolgus/Rhesus macaque FAK/PTK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T15068-Ag-1/ GM-Tg-felg-T15068-Ag-2 Feline FAK/PTK2 protein Feline
GM-Tg-cang-T15068-Ag-1/ GM-Tg-cang-T15068-Ag-2 Canine FAK/PTK2 protein Canine
GM-Tg-bovg-T15068-Ag-1/ GM-Tg-bovg-T15068-Ag-2 Bovine FAK/PTK2 protein Bovine
GM-Tg-equg-T15068-Ag-1/ GM-Tg-equg-T15068-Ag-2 Equine FAK/PTK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T15068-Ag-1/ GM-Tg-hg-T15068-Ag-2; GM-Tg-rg-T15068-Ag-1/ GM-Tg-rg-T15068-Ag-2;
GM-Tg-mg-T15068-Ag-1/ GM-Tg-mg-T15068-Ag-2; GM-Tg-cynog-T15068-Ag-1/ GM-Tg-cynog-T15068-Ag-2;
GM-Tg-felg-T15068-Ag-1/ GM-Tg-felg-T15068-Ag-2; GM-Tg-cang-T15068-Ag-1/ GM-Tg-cang-T15068-Ag-2;
GM-Tg-bovg-T15068-Ag-1/ GM-Tg-bovg-T15068-Ag-2; GM-Tg-equg-T15068-Ag-1/ GM-Tg-equg-T15068-Ag-2
Products Name FAK/PTK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FAK/PTK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FAK/PTK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.