Recombinant multi-species LDHA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LDHA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
The Alternative Names of target: CDK1,Cell proliferation-inducing gene 19 protein,GSD11,HEL-S-133P,L-lactate dehydrogenase A chain,LDH muscle subunit (LDH-M),LDH-A,LDHA,LDHM,Ldh1,Ldha,Ldhm,PIG19,Renal carcinoma antigen NY-REN-59,l7R2

Target products collectionGo to LDHA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T15053-Ag-1/ GM-Tg-hg-T15053-Ag-2 Human LDHA protein Human
GM-Tg-rg-T15053-Ag-1/ GM-Tg-rg-T15053-Ag-2 Rat LDHA protein Rat
GM-Tg-mg-T15053-Ag-1/ GM-Tg-mg-T15053-Ag-2 Mouse LDHA protein Mouse
GM-Tg-cynog-T15053-Ag-1/ GM-Tg-cynog-T15053-Ag-2 Cynomolgus/Rhesus macaque LDHA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T15053-Ag-1/ GM-Tg-felg-T15053-Ag-2 Feline LDHA protein Feline
GM-Tg-cang-T15053-Ag-1/ GM-Tg-cang-T15053-Ag-2 Canine LDHA protein Canine
GM-Tg-bovg-T15053-Ag-1/ GM-Tg-bovg-T15053-Ag-2 Bovine LDHA protein Bovine
GM-Tg-equg-T15053-Ag-1/ GM-Tg-equg-T15053-Ag-2 Equine LDHA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T15053-Ag-1/ GM-Tg-hg-T15053-Ag-2; GM-Tg-rg-T15053-Ag-1/ GM-Tg-rg-T15053-Ag-2;
GM-Tg-mg-T15053-Ag-1/ GM-Tg-mg-T15053-Ag-2; GM-Tg-cynog-T15053-Ag-1/ GM-Tg-cynog-T15053-Ag-2;
GM-Tg-felg-T15053-Ag-1/ GM-Tg-felg-T15053-Ag-2; GM-Tg-cang-T15053-Ag-1/ GM-Tg-cang-T15053-Ag-2;
GM-Tg-bovg-T15053-Ag-1/ GM-Tg-bovg-T15053-Ag-2; GM-Tg-equg-T15053-Ag-1/ GM-Tg-equg-T15053-Ag-2
Products Name LDHA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LDHA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LDHA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.