Explore LDHA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
| Target ID |
GM-T15053
|
| Target Name |
LDHA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3939
|
| Gene ID |
100057016 (Equus caballus), 101100248 (Felis catus), 16828 (Mus musculus), 24533 (Rattus norvegicus) 3939 (Homo sapiens), 476882 (Canis lupus familiaris), 694309 (Macaca mulatta)
|
| Target Alternative Names |
CDK1,Cell proliferation-inducing gene 19 protein,GSD11,HEL-S-133P,L-lactate dehydrogenase A chain,LDH muscle subunit (LDH-M),LDH-A,LDHA,LDHM,Ldh1,Ldha,Ldhm,PIG19,Renal carcinoma antigen NY-REN-59,l7R2
|
| Uniprot Accession |
P06151,P04642,P00338
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, HIF-1 signaling pathway, Central carbon metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000020669, ENSMUSG00000063229, ENSG00000134333, ENSMMUG00000031024
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of LDHA cDNA Clones/ORF Plasmid
LDHA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3939 | Pre-made Human LDHA/LDHM/GSD11 siRNA oligo Duplex | 3939 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24533 | Pre-made Rat Ldha/CDK1/Ldh1 siRNA oligo Duplex | 24533 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16828 | Pre-made Mouse Ldha/Ldh1/Ldhm siRNA oligo Duplex | 16828 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694309 | Pre-made Cynomolgus/Rhesus macaque LDHA siRNA oligo Duplex | 694309 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100248 | Pre-made Cat/Feline LDHA siRNA oligo Duplex | 101100248 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476882 | Pre-made Dog/Canine LDHA siRNA oligo Duplex | 476882 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057016 | Pre-made Equine/Horse LDHA siRNA oligo Duplex | 100057016 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LDHA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15053-Ab | Human | Anti-Human LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15053-Ab | Rat | Anti-Rat LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15053-Ab | Mouse | Anti-Mouse LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15053-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15053-Ab | Cat/Feline | Anti-Cat/Feline LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15053-Ab | Dog/Canine | Anti-Dog/Canine LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15053-Ab | Equine/Horse | Anti-Equine/Horse LDHA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
LDHA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15053-Ag | Human | Human LDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T15053-Ag | Rat | Rat LDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T15053-Ag | Mouse | Mouse LDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T15053-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T15053-Ag | Cat/Feline | Cat/Feline LDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T15053-Ag | Dog/Canine | Dog/Canine LDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T15053-Ag | Equine/Horse | Equine/Horse LDHA recombinant protein | Mammalian cell | Detail |