Recombinant multi-species APRIL/TNFSF13/CD256 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APRIL/TNFSF13/CD256 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
The Alternative Names of target: 2310026N09Rik,A proliferation-inducing ligand (APRIL),APRIL,April,CD256,TALL-2,TALL2,TNF- and APOL-related leukocyte expressed ligand 2 (TALL-2),TNF-related death ligand 1 (TRDL-1),TNFSF13,TNLG7B,TRDL-1,Tall2,Tnfsf13,Tnlg7b,Trdl1,Tumor necrosis factor ligand superfamily member 13,UNQ383/PRO715,ZTNF2

Target products collectionGo to APRIL/TNFSF13/CD256 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T14676-Ag-1/ GM-Tg-hg-T14676-Ag-2 Human APRIL/TNFSF13/CD256 protein Human
GM-Tg-rg-T14676-Ag-1/ GM-Tg-rg-T14676-Ag-2 Rat APRIL/TNFSF13/CD256 protein Rat
GM-Tg-mg-T14676-Ag-1/ GM-Tg-mg-T14676-Ag-2 Mouse APRIL/TNFSF13/CD256 protein Mouse
GM-Tg-cynog-T14676-Ag-1/ GM-Tg-cynog-T14676-Ag-2 Cynomolgus/Rhesus macaque APRIL/TNFSF13/CD256 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T14676-Ag-1/ GM-Tg-felg-T14676-Ag-2 Feline APRIL/TNFSF13/CD256 protein Feline
GM-Tg-cang-T14676-Ag-1/ GM-Tg-cang-T14676-Ag-2 Canine APRIL/TNFSF13/CD256 protein Canine
GM-Tg-bovg-T14676-Ag-1/ GM-Tg-bovg-T14676-Ag-2 Bovine APRIL/TNFSF13/CD256 protein Bovine
GM-Tg-equg-T14676-Ag-1/ GM-Tg-equg-T14676-Ag-2 Equine APRIL/TNFSF13/CD256 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T14676-Ag-1/ GM-Tg-hg-T14676-Ag-2; GM-Tg-rg-T14676-Ag-1/ GM-Tg-rg-T14676-Ag-2;
GM-Tg-mg-T14676-Ag-1/ GM-Tg-mg-T14676-Ag-2; GM-Tg-cynog-T14676-Ag-1/ GM-Tg-cynog-T14676-Ag-2;
GM-Tg-felg-T14676-Ag-1/ GM-Tg-felg-T14676-Ag-2; GM-Tg-cang-T14676-Ag-1/ GM-Tg-cang-T14676-Ag-2;
GM-Tg-bovg-T14676-Ag-1/ GM-Tg-bovg-T14676-Ag-2; GM-Tg-equg-T14676-Ag-1/ GM-Tg-equg-T14676-Ag-2
Products Name APRIL/TNFSF13/CD256 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name APRIL/TNFSF13/CD256
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APRIL/TNFSF13/CD256 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.