Recombinant multi-species TPSAB1/Tryptase protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPSAB1/Tryptase protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]
The Alternative Names of target: TPS1,TPS2,TPSAB1,TPSB1,TPSB2,Tryptase,Tryptase I,Tryptase alpha-1,Tryptase alpha/beta-1,Tryptase-1,Tryptase-2

Target products collectionGo to TPSAB1/Tryptase products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T14558-Ag-1/ GM-Tg-hg-T14558-Ag-2 Human TPSAB1/Tryptase protein Human
GM-Tg-rg-T14558-Ag-1/ GM-Tg-rg-T14558-Ag-2 Rat TPSAB1/Tryptase protein Rat
GM-Tg-mg-T14558-Ag-1/ GM-Tg-mg-T14558-Ag-2 Mouse TPSAB1/Tryptase protein Mouse
GM-Tg-cynog-T14558-Ag-1/ GM-Tg-cynog-T14558-Ag-2 Cynomolgus/Rhesus macaque TPSAB1/Tryptase protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T14558-Ag-1/ GM-Tg-felg-T14558-Ag-2 Feline TPSAB1/Tryptase protein Feline
GM-Tg-cang-T14558-Ag-1/ GM-Tg-cang-T14558-Ag-2 Canine TPSAB1/Tryptase protein Canine
GM-Tg-bovg-T14558-Ag-1/ GM-Tg-bovg-T14558-Ag-2 Bovine TPSAB1/Tryptase protein Bovine
GM-Tg-equg-T14558-Ag-1/ GM-Tg-equg-T14558-Ag-2 Equine TPSAB1/Tryptase protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T14558-Ag-1/ GM-Tg-hg-T14558-Ag-2; GM-Tg-rg-T14558-Ag-1/ GM-Tg-rg-T14558-Ag-2;
GM-Tg-mg-T14558-Ag-1/ GM-Tg-mg-T14558-Ag-2; GM-Tg-cynog-T14558-Ag-1/ GM-Tg-cynog-T14558-Ag-2;
GM-Tg-felg-T14558-Ag-1/ GM-Tg-felg-T14558-Ag-2; GM-Tg-cang-T14558-Ag-1/ GM-Tg-cang-T14558-Ag-2;
GM-Tg-bovg-T14558-Ag-1/ GM-Tg-bovg-T14558-Ag-2; GM-Tg-equg-T14558-Ag-1/ GM-Tg-equg-T14558-Ag-2
Products Name TPSAB1/Tryptase protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPSAB1/Tryptase
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPSAB1/Tryptase protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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