Recombinant multi-species RXRA/ORF-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RXRA/ORF-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
The Alternative Names of target: 9530071D11Rik,NR2B1,Nr2b1,Nuclear receptor subfamily 2 group B member 1,ORF-3,RXR-alpha,RXRA,RXRalpha,RXRalpha1,Retinoic acid receptor RXR-alpha,Retinoid X receptor alpha,Rxra
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T13726-Ag-1/ GM-Tg-hg-T13726-Ag-2 | Human RXRA/ORF-3 protein | Human |
| GM-Tg-rg-T13726-Ag-1/ GM-Tg-rg-T13726-Ag-2 | Rat RXRA/ORF-3 protein | Rat |
| GM-Tg-mg-T13726-Ag-1/ GM-Tg-mg-T13726-Ag-2 | Mouse RXRA/ORF-3 protein | Mouse |
| GM-Tg-cynog-T13726-Ag-1/ GM-Tg-cynog-T13726-Ag-2 | Cynomolgus/Rhesus macaque RXRA/ORF-3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T13726-Ag-1/ GM-Tg-felg-T13726-Ag-2 | Feline RXRA/ORF-3 protein | Feline |
| GM-Tg-cang-T13726-Ag-1/ GM-Tg-cang-T13726-Ag-2 | Canine RXRA/ORF-3 protein | Canine |
| GM-Tg-bovg-T13726-Ag-1/ GM-Tg-bovg-T13726-Ag-2 | Bovine RXRA/ORF-3 protein | Bovine |
| GM-Tg-equg-T13726-Ag-1/ GM-Tg-equg-T13726-Ag-2 | Equine RXRA/ORF-3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T13726-Ag-1/ GM-Tg-hg-T13726-Ag-2;
GM-Tg-rg-T13726-Ag-1/ GM-Tg-rg-T13726-Ag-2;
GM-Tg-mg-T13726-Ag-1/ GM-Tg-mg-T13726-Ag-2; GM-Tg-cynog-T13726-Ag-1/ GM-Tg-cynog-T13726-Ag-2; GM-Tg-felg-T13726-Ag-1/ GM-Tg-felg-T13726-Ag-2; GM-Tg-cang-T13726-Ag-1/ GM-Tg-cang-T13726-Ag-2; GM-Tg-bovg-T13726-Ag-1/ GM-Tg-bovg-T13726-Ag-2; GM-Tg-equg-T13726-Ag-1/ GM-Tg-equg-T13726-Ag-2 |
| Products Name | RXRA/ORF-3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RXRA/ORF-3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RXRA/ORF-3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.