Recombinant multi-species RXRA/ORF-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RXRA/ORF-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
The Alternative Names of target: 9530071D11Rik,NR2B1,Nr2b1,Nuclear receptor subfamily 2 group B member 1,ORF-3,RXR-alpha,RXRA,RXRalpha,RXRalpha1,Retinoic acid receptor RXR-alpha,Retinoid X receptor alpha,Rxra

Target products collectionGo to RXRA/ORF-3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T13726-Ag-1/ GM-Tg-hg-T13726-Ag-2 Human RXRA/ORF-3 protein Human
GM-Tg-rg-T13726-Ag-1/ GM-Tg-rg-T13726-Ag-2 Rat RXRA/ORF-3 protein Rat
GM-Tg-mg-T13726-Ag-1/ GM-Tg-mg-T13726-Ag-2 Mouse RXRA/ORF-3 protein Mouse
GM-Tg-cynog-T13726-Ag-1/ GM-Tg-cynog-T13726-Ag-2 Cynomolgus/Rhesus macaque RXRA/ORF-3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T13726-Ag-1/ GM-Tg-felg-T13726-Ag-2 Feline RXRA/ORF-3 protein Feline
GM-Tg-cang-T13726-Ag-1/ GM-Tg-cang-T13726-Ag-2 Canine RXRA/ORF-3 protein Canine
GM-Tg-bovg-T13726-Ag-1/ GM-Tg-bovg-T13726-Ag-2 Bovine RXRA/ORF-3 protein Bovine
GM-Tg-equg-T13726-Ag-1/ GM-Tg-equg-T13726-Ag-2 Equine RXRA/ORF-3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T13726-Ag-1/ GM-Tg-hg-T13726-Ag-2; GM-Tg-rg-T13726-Ag-1/ GM-Tg-rg-T13726-Ag-2;
GM-Tg-mg-T13726-Ag-1/ GM-Tg-mg-T13726-Ag-2; GM-Tg-cynog-T13726-Ag-1/ GM-Tg-cynog-T13726-Ag-2;
GM-Tg-felg-T13726-Ag-1/ GM-Tg-felg-T13726-Ag-2; GM-Tg-cang-T13726-Ag-1/ GM-Tg-cang-T13726-Ag-2;
GM-Tg-bovg-T13726-Ag-1/ GM-Tg-bovg-T13726-Ag-2; GM-Tg-equg-T13726-Ag-1/ GM-Tg-equg-T13726-Ag-2
Products Name RXRA/ORF-3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RXRA/ORF-3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RXRA/ORF-3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.