Explore RXRA/ORF-3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
| Target ID |
GM-T13726
|
| Target Name |
RXRA/ORF-3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6256
|
| Gene ID |
100069096 (Equus caballus), 101085757 (Felis catus), 20181 (Mus musculus), 25271 (Rattus norvegicus) 491278 (Canis lupus familiaris), 507554 (Bos taurus), 6256 (Homo sapiens), 722068 (Macaca mulatta)
|
| Target Alternative Names |
9530071D11Rik,NR2B1,Nr2b1,Nuclear receptor subfamily 2 group B member 1,ORF-3,RXR-alpha,RXRA,RXRalpha,RXRalpha1,Retinoic acid receptor RXR-alpha,Retinoid X receptor alpha,Rxra
|
| Uniprot Accession |
P28700,Q05343,P19793
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
PPAR signaling pathway, PI3K-Akt signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Parathyroid hormone synthesis, secretion and action, Bile secretion, Hepatitis C, Pathways in cancer, Chemical carcinogenesis - receptor activation, Thyroid cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000019365, ENSMUSG00000015846, ENSCAFG00845012191, ENSBTAG00000017851, ENSG00000186350, ENSMMUG00000008183
|
| Target Classification |
Nuclear Receptors, Tumor-associated antigen (TAA)
|
Pre-made viral vector of RXRA/ORF-3 cDNA Clones/ORF Plasmid
RXRA/ORF-3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6256 | Pre-made Human RXRA/NR2B1/RXRalpha siRNA oligo Duplex | 6256 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25271 | Pre-made Rat Rxra siRNA oligo Duplex | 25271 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20181 | Pre-made Mouse Rxra/Nr2b1/RXRalpha1 siRNA oligo Duplex | 20181 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722068 | Pre-made Cynomolgus/Rhesus macaque RXRA siRNA oligo Duplex | 722068 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085757 | Pre-made Cat/Feline RXRA siRNA oligo Duplex | 101085757 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491278 | Pre-made Dog/Canine RXRA/RXRalpha siRNA oligo Duplex | 491278 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507554 | Pre-made Bovines/Cattle RXRA siRNA oligo Duplex | 507554 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069096 | Pre-made Equine/Horse RXRA siRNA oligo Duplex | 100069096 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RXRA/ORF-3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13726-Ab | Human | Anti-Human RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T13726-Ab | Rat | Anti-Rat RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T13726-Ab | Mouse | Anti-Mouse RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T13726-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T13726-Ab | Cat/Feline | Anti-Cat/Feline RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T13726-Ab | Dog/Canine | Anti-Dog/Canine RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T13726-Ab | Bovines/Cattle | Anti-Bovines/Cattle RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T13726-Ab | Equine/Horse | Anti-Equine/Horse RXRA/ORF-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RXRA/ORF-3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13726-Ag | Human | Human RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T13726-Ag | Rat | Rat RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T13726-Ag | Mouse | Mouse RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T13726-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T13726-Ag | Cat/Feline | Cat/Feline RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T13726-Ag | Dog/Canine | Dog/Canine RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T13726-Ag | Bovines/Cattle | Bovines/Cattle RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T13726-Ag | Equine/Horse | Equine/Horse RXRA/ORF-3 recombinant protein | Mammalian cell | Detail |