Recombinant multi-species TNNC1/TN-C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNC1/TN-C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
The Alternative Names of target: CMD1Z,CMH13,TN-C,TNC,TNNC,TNNC1,TnC,Tncc,Tnnc1,Troponin C,cTnC,cTnI,slow skeletal and cardiac muscles,tncc
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T12966-Ag-1/ GM-Tg-hg-T12966-Ag-2 | Human TNNC1/TN-C protein | Human |
| GM-Tg-rg-T12966-Ag-1/ GM-Tg-rg-T12966-Ag-2 | Rat TNNC1/TN-C protein | Rat |
| GM-Tg-mg-T12966-Ag-1/ GM-Tg-mg-T12966-Ag-2 | Mouse TNNC1/TN-C protein | Mouse |
| GM-Tg-cynog-T12966-Ag-1/ GM-Tg-cynog-T12966-Ag-2 | Cynomolgus/Rhesus macaque TNNC1/TN-C protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T12966-Ag-1/ GM-Tg-felg-T12966-Ag-2 | Feline TNNC1/TN-C protein | Feline |
| GM-Tg-cang-T12966-Ag-1/ GM-Tg-cang-T12966-Ag-2 | Canine TNNC1/TN-C protein | Canine |
| GM-Tg-bovg-T12966-Ag-1/ GM-Tg-bovg-T12966-Ag-2 | Bovine TNNC1/TN-C protein | Bovine |
| GM-Tg-equg-T12966-Ag-1/ GM-Tg-equg-T12966-Ag-2 | Equine TNNC1/TN-C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T12966-Ag-1/ GM-Tg-hg-T12966-Ag-2;
GM-Tg-rg-T12966-Ag-1/ GM-Tg-rg-T12966-Ag-2;
GM-Tg-mg-T12966-Ag-1/ GM-Tg-mg-T12966-Ag-2; GM-Tg-cynog-T12966-Ag-1/ GM-Tg-cynog-T12966-Ag-2; GM-Tg-felg-T12966-Ag-1/ GM-Tg-felg-T12966-Ag-2; GM-Tg-cang-T12966-Ag-1/ GM-Tg-cang-T12966-Ag-2; GM-Tg-bovg-T12966-Ag-1/ GM-Tg-bovg-T12966-Ag-2; GM-Tg-equg-T12966-Ag-1/ GM-Tg-equg-T12966-Ag-2 |
| Products Name | TNNC1/TN-C protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | TNNC1/TN-C |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNC1/TN-C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.