Recombinant multi-species TNNC1/TN-C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNC1/TN-C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
The Alternative Names of target: CMD1Z,CMH13,TN-C,TNC,TNNC,TNNC1,TnC,Tncc,Tnnc1,Troponin C,cTnC,cTnI,slow skeletal and cardiac muscles,tncc

Target products collectionGo to TNNC1/TN-C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T12966-Ag-1/ GM-Tg-hg-T12966-Ag-2 Human TNNC1/TN-C protein Human
GM-Tg-rg-T12966-Ag-1/ GM-Tg-rg-T12966-Ag-2 Rat TNNC1/TN-C protein Rat
GM-Tg-mg-T12966-Ag-1/ GM-Tg-mg-T12966-Ag-2 Mouse TNNC1/TN-C protein Mouse
GM-Tg-cynog-T12966-Ag-1/ GM-Tg-cynog-T12966-Ag-2 Cynomolgus/Rhesus macaque TNNC1/TN-C protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T12966-Ag-1/ GM-Tg-felg-T12966-Ag-2 Feline TNNC1/TN-C protein Feline
GM-Tg-cang-T12966-Ag-1/ GM-Tg-cang-T12966-Ag-2 Canine TNNC1/TN-C protein Canine
GM-Tg-bovg-T12966-Ag-1/ GM-Tg-bovg-T12966-Ag-2 Bovine TNNC1/TN-C protein Bovine
GM-Tg-equg-T12966-Ag-1/ GM-Tg-equg-T12966-Ag-2 Equine TNNC1/TN-C protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T12966-Ag-1/ GM-Tg-hg-T12966-Ag-2; GM-Tg-rg-T12966-Ag-1/ GM-Tg-rg-T12966-Ag-2;
GM-Tg-mg-T12966-Ag-1/ GM-Tg-mg-T12966-Ag-2; GM-Tg-cynog-T12966-Ag-1/ GM-Tg-cynog-T12966-Ag-2;
GM-Tg-felg-T12966-Ag-1/ GM-Tg-felg-T12966-Ag-2; GM-Tg-cang-T12966-Ag-1/ GM-Tg-cang-T12966-Ag-2;
GM-Tg-bovg-T12966-Ag-1/ GM-Tg-bovg-T12966-Ag-2; GM-Tg-equg-T12966-Ag-1/ GM-Tg-equg-T12966-Ag-2
Products Name TNNC1/TN-C protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TNNC1/TN-C
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNC1/TN-C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.