Recombinant multi-species VCP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VCP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017]
The Alternative Names of target: 15S Mg(2+)-ATPase p97 subunit,3110001E05,CDC48,FTDALS6,TER ATPase,TERA,Transitional endoplasmic reticulum ATPase,VCP,Valosin-containing protein (VCP),Vcp,p97,p97/VCP

Target products collectionGo to VCP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T12646-Ag-1/ GM-Tg-hg-T12646-Ag-2 Human VCP protein Human
GM-Tg-rg-T12646-Ag-1/ GM-Tg-rg-T12646-Ag-2 Rat VCP protein Rat
GM-Tg-mg-T12646-Ag-1/ GM-Tg-mg-T12646-Ag-2 Mouse VCP protein Mouse
GM-Tg-cynog-T12646-Ag-1/ GM-Tg-cynog-T12646-Ag-2 Cynomolgus/Rhesus macaque VCP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T12646-Ag-1/ GM-Tg-felg-T12646-Ag-2 Feline VCP protein Feline
GM-Tg-cang-T12646-Ag-1/ GM-Tg-cang-T12646-Ag-2 Canine VCP protein Canine
GM-Tg-bovg-T12646-Ag-1/ GM-Tg-bovg-T12646-Ag-2 Bovine VCP protein Bovine
GM-Tg-equg-T12646-Ag-1/ GM-Tg-equg-T12646-Ag-2 Equine VCP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T12646-Ag-1/ GM-Tg-hg-T12646-Ag-2; GM-Tg-rg-T12646-Ag-1/ GM-Tg-rg-T12646-Ag-2;
GM-Tg-mg-T12646-Ag-1/ GM-Tg-mg-T12646-Ag-2; GM-Tg-cynog-T12646-Ag-1/ GM-Tg-cynog-T12646-Ag-2;
GM-Tg-felg-T12646-Ag-1/ GM-Tg-felg-T12646-Ag-2; GM-Tg-cang-T12646-Ag-1/ GM-Tg-cang-T12646-Ag-2;
GM-Tg-bovg-T12646-Ag-1/ GM-Tg-bovg-T12646-Ag-2; GM-Tg-equg-T12646-Ag-1/ GM-Tg-equg-T12646-Ag-2
Products Name VCP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name VCP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VCP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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