Explore VCP gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T12646
|
| Target Name |
VCP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7415
|
| Gene ID |
100068225 (Equus caballus), 101091411 (Felis catus), 116643 (Rattus norvegicus), 269523 (Mus musculus)
481590 (Canis lupus familiaris), 507345 (Bos taurus), 698707 (Macaca mulatta), 7415 (Homo sapiens)
|
| Target Alternative Names |
15S Mg(2+)-ATPase p97 subunit,3110001E05,CDC48,FTDALS6,TER ATPase,TERA,Transitional endoplasmic reticulum ATPase,VCP,Valosin-containing protein (VCP),Vcp,p97,p97/VCP
|
| Uniprot Accession |
P46462,Q01853,Q3ZBT1,P55072
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, Legionellosis
|
| Gene Ensembl |
ENSECAG00000010644, ENSMUSG00000028452, ENSCAFG00845005647, ENSBTAG00000015000, ENSMMUG00000020190, ENSG00000165280
|
Pre-made viral vector of VCP cDNA Clones/ORF Plasmid
VCP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7415 | Pre-made Human VCP/p97/TERA siRNA oligo Duplex | 7415 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116643 | Pre-made Rat Vcp siRNA oligo Duplex | 116643 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo269523 | Pre-made Mouse Vcp/p97/CDC48 siRNA oligo Duplex | 269523 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698707 | Pre-made Cynomolgus/Rhesus macaque VCP siRNA oligo Duplex | 698707 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091411 | Pre-made Cat/Feline VCP siRNA oligo Duplex | 101091411 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481590 | Pre-made Dog/Canine VCP siRNA oligo Duplex | 481590 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507345 | Pre-made Bovines/Cattle VCP/p97 siRNA oligo Duplex | 507345 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068225 | Pre-made Equine/Horse VCP siRNA oligo Duplex | 100068225 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VCP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T12646-Ab | Human | Anti-Human VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T12646-Ab | Rat | Anti-Rat VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T12646-Ab | Mouse | Anti-Mouse VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T12646-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T12646-Ab | Cat/Feline | Anti-Cat/Feline VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T12646-Ab | Dog/Canine | Anti-Dog/Canine VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T12646-Ab | Bovines/Cattle | Anti-Bovines/Cattle VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T12646-Ab | Equine/Horse | Anti-Equine/Horse VCP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
VCP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T12646-Ag | Human | Human VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T12646-Ag | Rat | Rat VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T12646-Ag | Mouse | Mouse VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T12646-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T12646-Ag | Cat/Feline | Cat/Feline VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T12646-Ag | Dog/Canine | Dog/Canine VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T12646-Ag | Bovines/Cattle | Bovines/Cattle VCP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T12646-Ag | Equine/Horse | Equine/Horse VCP recombinant protein | Mammalian cell | Detail |
