Recombinant multi-species PDE4C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE4C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
The Alternative Names of target: 3',5'-cyclic-AMP phosphodiesterase 4C,DPDE1,Dpde1,E130301F19Rik,PDE21,PDE4C,Pde4c,cAMP-specific phosphodiesterase 4C,dunce

Target products collectionGo to PDE4C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T12081-Ag-1/ GM-Tg-hg-T12081-Ag-2 Human PDE4C protein Human
GM-Tg-rg-T12081-Ag-1/ GM-Tg-rg-T12081-Ag-2 Rat PDE4C protein Rat
GM-Tg-mg-T12081-Ag-1/ GM-Tg-mg-T12081-Ag-2 Mouse PDE4C protein Mouse
GM-Tg-cynog-T12081-Ag-1/ GM-Tg-cynog-T12081-Ag-2 Cynomolgus/Rhesus macaque PDE4C protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T12081-Ag-1/ GM-Tg-felg-T12081-Ag-2 Feline PDE4C protein Feline
GM-Tg-cang-T12081-Ag-1/ GM-Tg-cang-T12081-Ag-2 Canine PDE4C protein Canine
GM-Tg-bovg-T12081-Ag-1/ GM-Tg-bovg-T12081-Ag-2 Bovine PDE4C protein Bovine
GM-Tg-equg-T12081-Ag-1/ GM-Tg-equg-T12081-Ag-2 Equine PDE4C protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T12081-Ag-1/ GM-Tg-hg-T12081-Ag-2; GM-Tg-rg-T12081-Ag-1/ GM-Tg-rg-T12081-Ag-2;
GM-Tg-mg-T12081-Ag-1/ GM-Tg-mg-T12081-Ag-2; GM-Tg-cynog-T12081-Ag-1/ GM-Tg-cynog-T12081-Ag-2;
GM-Tg-felg-T12081-Ag-1/ GM-Tg-felg-T12081-Ag-2; GM-Tg-cang-T12081-Ag-1/ GM-Tg-cang-T12081-Ag-2;
GM-Tg-bovg-T12081-Ag-1/ GM-Tg-bovg-T12081-Ag-2; GM-Tg-equg-T12081-Ag-1/ GM-Tg-equg-T12081-Ag-2
Products Name PDE4C protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PDE4C
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE4C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.