Explore PDE4C gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
| Target ID |
GM-T12081
|
| Target Name |
PDE4C
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5143
|
| Gene ID |
100070899 (Equus caballus), 101086123 (Felis catus), 110385 (Mus musculus), 290646 (Rattus norvegicus)
5143 (Homo sapiens), 524624 (Bos taurus), 609938 (Canis lupus familiaris), 720171 (Macaca mulatta)
|
| Target Alternative Names |
3',5'-cyclic-AMP phosphodiesterase 4C,DPDE1,Dpde1,E130301F19Rik,PDE21,PDE4C,Pde4c,cAMP-specific phosphodiesterase 4C,dunce
|
| Uniprot Accession |
Q3UEI1,P14644,Q08493
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000008059, ENSMUSG00000031842, ENSG00000105650, ENSBTAG00000010652, ENSCAFG00845022978, ENSMMUG00000005028
|
PDE4C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5143 | Pre-made Human PDE4C/DPDE1/PDE21 siRNA oligo Duplex | 5143 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo290646 | Pre-made Rat Pde4c/Dpde1 siRNA oligo Duplex | 290646 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110385 | Pre-made Mouse Pde4c/Dpde1/dunce siRNA oligo Duplex | 110385 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720171 | Pre-made Cynomolgus/Rhesus macaque PDE4C siRNA oligo Duplex | 720171 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086123 | Pre-made Cat/Feline PDE4C siRNA oligo Duplex | 101086123 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609938 | Pre-made Dog/Canine PDE4C siRNA oligo Duplex | 609938 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524624 | Pre-made Bovines/Cattle PDE4C siRNA oligo Duplex | 524624 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070899 | Pre-made Equine/Horse PDE4C siRNA oligo Duplex | 100070899 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDE4C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T12081-Ab | Human | Anti-Human PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T12081-Ab | Rat | Anti-Rat PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T12081-Ab | Mouse | Anti-Mouse PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T12081-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T12081-Ab | Cat/Feline | Anti-Cat/Feline PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T12081-Ab | Dog/Canine | Anti-Dog/Canine PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T12081-Ab | Bovines/Cattle | Anti-Bovines/Cattle PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T12081-Ab | Equine/Horse | Anti-Equine/Horse PDE4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PDE4C recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T12081-Ag | Human | Human PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T12081-Ag | Rat | Rat PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T12081-Ag | Mouse | Mouse PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T12081-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T12081-Ag | Cat/Feline | Cat/Feline PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T12081-Ag | Dog/Canine | Dog/Canine PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T12081-Ag | Bovines/Cattle | Bovines/Cattle PDE4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T12081-Ag | Equine/Horse | Equine/Horse PDE4C recombinant protein | Mammalian cell | Detail |
