Recombinant multi-species Cathepsin K/CTSK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cathepsin K/CTSK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
The Alternative Names of target: CTS02,CTSK,CTSO,CTSO1,CTSO2,Cathepsin K,Cathepsin O,Cathepsin O2,Cathepsin X,Ctsk,MMS10-Q,Ms10q,PKND,PYCD,catK

Target products collectionGo to Cathepsin K/CTSK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T11388-Ag-1/ GM-Tg-hg-T11388-Ag-2 Human Cathepsin K/CTSK protein Human
GM-Tg-rg-T11388-Ag-1/ GM-Tg-rg-T11388-Ag-2 Rat Cathepsin K/CTSK protein Rat
GM-Tg-mg-T11388-Ag-1/ GM-Tg-mg-T11388-Ag-2 Mouse Cathepsin K/CTSK protein Mouse
GM-Tg-cynog-T11388-Ag-1/ GM-Tg-cynog-T11388-Ag-2 Cynomolgus/Rhesus macaque Cathepsin K/CTSK protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T11388-Ag-1/ GM-Tg-felg-T11388-Ag-2 Feline Cathepsin K/CTSK protein Feline
GM-Tg-cang-T11388-Ag-1/ GM-Tg-cang-T11388-Ag-2 Canine Cathepsin K/CTSK protein Canine
GM-Tg-bovg-T11388-Ag-1/ GM-Tg-bovg-T11388-Ag-2 Bovine Cathepsin K/CTSK protein Bovine
GM-Tg-equg-T11388-Ag-1/ GM-Tg-equg-T11388-Ag-2 Equine Cathepsin K/CTSK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T11388-Ag-1/ GM-Tg-hg-T11388-Ag-2; GM-Tg-rg-T11388-Ag-1/ GM-Tg-rg-T11388-Ag-2;
GM-Tg-mg-T11388-Ag-1/ GM-Tg-mg-T11388-Ag-2; GM-Tg-cynog-T11388-Ag-1/ GM-Tg-cynog-T11388-Ag-2;
GM-Tg-felg-T11388-Ag-1/ GM-Tg-felg-T11388-Ag-2; GM-Tg-cang-T11388-Ag-1/ GM-Tg-cang-T11388-Ag-2;
GM-Tg-bovg-T11388-Ag-1/ GM-Tg-bovg-T11388-Ag-2; GM-Tg-equg-T11388-Ag-1/ GM-Tg-equg-T11388-Ag-2
Products Name Cathepsin K/CTSK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cathepsin K/CTSK
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cathepsin K/CTSK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.