Explore Cathepsin K/CTSK gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
| Target ID |
GM-T11388
|
| Target Name |
Cathepsin K/CTSK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1513
|
| Gene ID |
100054991 (Equus caballus), 101093379 (Felis catus), 13038 (Mus musculus), 1513 (Homo sapiens)
29175 (Rattus norvegicus), 513038 (Bos taurus), 574112 (Macaca mulatta), 608843 (Canis lupus familiaris)
|
| Target Alternative Names |
CTS02,CTSK,CTSO,CTSO1,CTSO2,Cathepsin K,Cathepsin O,Cathepsin O2,Cathepsin X,Ctsk,MMS10-Q,Ms10q,PKND,PYCD,catK
|
| Uniprot Accession |
P55097,P43235,O35186,Q5E968,P61277,Q3ZKN1
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Lysosome, Apoptosis, Osteoclast differentiation, Toll-like receptor signaling pathway, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000019087, ENSMUSG00000028111, ENSG00000143387, ENSBTAG00000021035, ENSCAFG00845019461
|
Pre-made viral vector of Cathepsin K/CTSK cDNA Clones/ORF Plasmid
Cathepsin K/CTSK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1513 | Pre-made Human CTSK/CTSO/PKND siRNA oligo Duplex | 1513 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29175 | Pre-made Rat Ctsk siRNA oligo Duplex | 29175 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13038 | Pre-made Mouse Ctsk/catK/Ms10q siRNA oligo Duplex | 13038 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574112 | Pre-made Cynomolgus/Rhesus macaque CTSK siRNA oligo Duplex | 574112 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093379 | Pre-made Cat/Feline CTSK siRNA oligo Duplex | 101093379 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608843 | Pre-made Dog/Canine CTSK siRNA oligo Duplex | 608843 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513038 | Pre-made Bovines/Cattle CTSK siRNA oligo Duplex | 513038 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054991 | Pre-made Equine/Horse CTSK siRNA oligo Duplex | 100054991 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cathepsin K/CTSK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11388-Ab | Human | Anti-Human Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T11388-Ab | Rat | Anti-Rat Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T11388-Ab | Mouse | Anti-Mouse Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T11388-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T11388-Ab | Cat/Feline | Anti-Cat/Feline Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T11388-Ab | Dog/Canine | Anti-Dog/Canine Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T11388-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T11388-Ab | Equine/Horse | Anti-Equine/Horse Cathepsin K/CTSK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Cathepsin K/CTSK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11388-Ag | Human | Human Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T11388-Ag | Rat | Rat Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T11388-Ag | Mouse | Mouse Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T11388-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T11388-Ag | Cat/Feline | Cat/Feline Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T11388-Ag | Dog/Canine | Dog/Canine Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T11388-Ag | Bovines/Cattle | Bovines/Cattle Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T11388-Ag | Equine/Horse | Equine/Horse Cathepsin K/CTSK recombinant protein | Mammalian cell | Detail |
