Recombinant multi-species MCP-1/CCL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MCP-1/CCL2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
The Alternative Names of target: C-C motif chemokine 2,CCL2,Ccl2,GDCF-2,HC11,HSMCR30,JE,MCAF,MCP-1,MCP1,Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor (MCAF),Monocyte chemotactic protein 1 (MCP-1),Monocyte secretory protein JE,SCYA2,SMC-CF,Scya2,Sigje,Small-inducible cytokine A2

Target products collectionGo to MCP-1/CCL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T11309-Ag-1/ GM-Tg-hg-T11309-Ag-2 Human MCP-1/CCL2 protein Human
GM-Tg-rg-T11309-Ag-1/ GM-Tg-rg-T11309-Ag-2 Rat MCP-1/CCL2 protein Rat
GM-Tg-mg-T11309-Ag-1/ GM-Tg-mg-T11309-Ag-2 Mouse MCP-1/CCL2 protein Mouse
GM-Tg-cynog-T11309-Ag-1/ GM-Tg-cynog-T11309-Ag-2 Cynomolgus/Rhesus macaque MCP-1/CCL2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T11309-Ag-1/ GM-Tg-felg-T11309-Ag-2 Feline MCP-1/CCL2 protein Feline
GM-Tg-cang-T11309-Ag-1/ GM-Tg-cang-T11309-Ag-2 Canine MCP-1/CCL2 protein Canine
GM-Tg-bovg-T11309-Ag-1/ GM-Tg-bovg-T11309-Ag-2 Bovine MCP-1/CCL2 protein Bovine
GM-Tg-equg-T11309-Ag-1/ GM-Tg-equg-T11309-Ag-2 Equine MCP-1/CCL2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T11309-Ag-1/ GM-Tg-hg-T11309-Ag-2; GM-Tg-rg-T11309-Ag-1/ GM-Tg-rg-T11309-Ag-2;
GM-Tg-mg-T11309-Ag-1/ GM-Tg-mg-T11309-Ag-2; GM-Tg-cynog-T11309-Ag-1/ GM-Tg-cynog-T11309-Ag-2;
GM-Tg-felg-T11309-Ag-1/ GM-Tg-felg-T11309-Ag-2; GM-Tg-cang-T11309-Ag-1/ GM-Tg-cang-T11309-Ag-2;
GM-Tg-bovg-T11309-Ag-1/ GM-Tg-bovg-T11309-Ag-2; GM-Tg-equg-T11309-Ag-1/ GM-Tg-equg-T11309-Ag-2
Products Name MCP-1/CCL2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MCP-1/CCL2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MCP-1/CCL2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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