Recombinant multi-species AFP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AFP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
The Alternative Names of target: AFP,AFPD,Afp,Alpha-1-fetoprotein,Alpha-fetoglobulin,Alpha-fetoprotein,FETA,HPAFP

Target products collectionGo to AFP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T10828-Ag-1/ GM-Tg-hg-T10828-Ag-2 Human AFP protein Human
GM-Tg-rg-T10828-Ag-1/ GM-Tg-rg-T10828-Ag-2 Rat AFP protein Rat
GM-Tg-mg-T10828-Ag-1/ GM-Tg-mg-T10828-Ag-2 Mouse AFP protein Mouse
GM-Tg-cynog-T10828-Ag-1/ GM-Tg-cynog-T10828-Ag-2 Cynomolgus/Rhesus macaque AFP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T10828-Ag-1/ GM-Tg-felg-T10828-Ag-2 Feline AFP protein Feline
GM-Tg-cang-T10828-Ag-1/ GM-Tg-cang-T10828-Ag-2 Canine AFP protein Canine
GM-Tg-bovg-T10828-Ag-1/ GM-Tg-bovg-T10828-Ag-2 Bovine AFP protein Bovine
GM-Tg-equg-T10828-Ag-1/ GM-Tg-equg-T10828-Ag-2 Equine AFP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T10828-Ag-1/ GM-Tg-hg-T10828-Ag-2; GM-Tg-rg-T10828-Ag-1/ GM-Tg-rg-T10828-Ag-2;
GM-Tg-mg-T10828-Ag-1/ GM-Tg-mg-T10828-Ag-2; GM-Tg-cynog-T10828-Ag-1/ GM-Tg-cynog-T10828-Ag-2;
GM-Tg-felg-T10828-Ag-1/ GM-Tg-felg-T10828-Ag-2; GM-Tg-cang-T10828-Ag-1/ GM-Tg-cang-T10828-Ag-2;
GM-Tg-bovg-T10828-Ag-1/ GM-Tg-bovg-T10828-Ag-2; GM-Tg-equg-T10828-Ag-1/ GM-Tg-equg-T10828-Ag-2
Products Name AFP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AFP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AFP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.