Recombinant multi-species DKK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DKK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
The Alternative Names of target: DKK-2,DKK2,Dickkopf-2,Dickkopf-related protein 2,Dkk-2,Dkk2,hDkk-2

Target products collectionGo to DKK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T10125-Ag-1/ GM-Tg-hg-T10125-Ag-2 Human DKK2 protein Human
GM-Tg-rg-T10125-Ag-1/ GM-Tg-rg-T10125-Ag-2 Rat DKK2 protein Rat
GM-Tg-mg-T10125-Ag-1/ GM-Tg-mg-T10125-Ag-2 Mouse DKK2 protein Mouse
GM-Tg-cynog-T10125-Ag-1/ GM-Tg-cynog-T10125-Ag-2 Cynomolgus/Rhesus macaque DKK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T10125-Ag-1/ GM-Tg-felg-T10125-Ag-2 Feline DKK2 protein Feline
GM-Tg-cang-T10125-Ag-1/ GM-Tg-cang-T10125-Ag-2 Canine DKK2 protein Canine
GM-Tg-bovg-T10125-Ag-1/ GM-Tg-bovg-T10125-Ag-2 Bovine DKK2 protein Bovine
GM-Tg-equg-T10125-Ag-1/ GM-Tg-equg-T10125-Ag-2 Equine DKK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T10125-Ag-1/ GM-Tg-hg-T10125-Ag-2; GM-Tg-rg-T10125-Ag-1/ GM-Tg-rg-T10125-Ag-2;
GM-Tg-mg-T10125-Ag-1/ GM-Tg-mg-T10125-Ag-2; GM-Tg-cynog-T10125-Ag-1/ GM-Tg-cynog-T10125-Ag-2;
GM-Tg-felg-T10125-Ag-1/ GM-Tg-felg-T10125-Ag-2; GM-Tg-cang-T10125-Ag-1/ GM-Tg-cang-T10125-Ag-2;
GM-Tg-bovg-T10125-Ag-1/ GM-Tg-bovg-T10125-Ag-2; GM-Tg-equg-T10125-Ag-1/ GM-Tg-equg-T10125-Ag-2
Products Name DKK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DKK2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DKK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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