Recombinant multi-species MMP8/MMP-8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP8/MMP-8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
The Alternative Names of target: CLG1,HNC,MMP-8,MMP8,Matrix metalloproteinase-8 (MMP-8),Mmp8,Neutrophil collagenase,PMNL collagenase (PMNL-CL),PMNL-CL

Target products collectionGo to MMP8/MMP-8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T08856-Ag-1/ GM-Tg-hg-T08856-Ag-2 Human MMP8/MMP-8 protein Human
GM-Tg-rg-T08856-Ag-1/ GM-Tg-rg-T08856-Ag-2 Rat MMP8/MMP-8 protein Rat
GM-Tg-mg-T08856-Ag-1/ GM-Tg-mg-T08856-Ag-2 Mouse MMP8/MMP-8 protein Mouse
GM-Tg-cynog-T08856-Ag-1/ GM-Tg-cynog-T08856-Ag-2 Cynomolgus/Rhesus macaque MMP8/MMP-8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T08856-Ag-1/ GM-Tg-felg-T08856-Ag-2 Feline MMP8/MMP-8 protein Feline
GM-Tg-cang-T08856-Ag-1/ GM-Tg-cang-T08856-Ag-2 Canine MMP8/MMP-8 protein Canine
GM-Tg-bovg-T08856-Ag-1/ GM-Tg-bovg-T08856-Ag-2 Bovine MMP8/MMP-8 protein Bovine
GM-Tg-equg-T08856-Ag-1/ GM-Tg-equg-T08856-Ag-2 Equine MMP8/MMP-8 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T08856-Ag-1/ GM-Tg-hg-T08856-Ag-2; GM-Tg-rg-T08856-Ag-1/ GM-Tg-rg-T08856-Ag-2;
GM-Tg-mg-T08856-Ag-1/ GM-Tg-mg-T08856-Ag-2; GM-Tg-cynog-T08856-Ag-1/ GM-Tg-cynog-T08856-Ag-2;
GM-Tg-felg-T08856-Ag-1/ GM-Tg-felg-T08856-Ag-2; GM-Tg-cang-T08856-Ag-1/ GM-Tg-cang-T08856-Ag-2;
GM-Tg-bovg-T08856-Ag-1/ GM-Tg-bovg-T08856-Ag-2; GM-Tg-equg-T08856-Ag-1/ GM-Tg-equg-T08856-Ag-2
Products Name MMP8/MMP-8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MMP8/MMP-8
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MMP8/MMP-8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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